Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297801 | 0.87 | KIF11 (0.54) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL289976 | 0.81 | KIF11 (0.48) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL6900832 | 0.81 | KIF11 (0.48) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL18355972 | 0.79 | KIF11 (0.46) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL22212787 | 0.79 | KIF11 (0.46) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL19309077 | 0.79 | KIF11 (0.46) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL16207357 | 0.76 | KIF11 (0.43) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL3894118 | 0.74 | CYP3A4 (0.45) | MAPTALDH1A1TDP1KDM4EMAPK1 | |
| Propane SCHEMBL28874741 | 0.74 | KIF11 (0.42) | KIF11MAOBMAPTMEN1KMT2A | |
| SCHEMBL5846633 | 0.73 | CA12 (0.37) | ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041852-B2 | Perfluoroalkylanilines | BAYER CHEMICALS AG (DE) | 2006-05-09 | — | — | US | claimed |
| US-20040152898-A1 | Perfluoroalkylanilines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-05 | — | — | US | claimed |
| EP-1418171-A1 | Perfluoroalkylanilins | Bayer Chemicals AG (DE) | 2004-05-12 | — | — | EP | claimed |
| EP-3556744-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-06-01 | — | — | EP | disclosed |
| EP-3087052-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-20 | — | — | EP | disclosed |
| EP-3556744-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-23 | — | — | EP | disclosed |
| US-9750246-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-9750246-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| EP-2456759-B1 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2017-04-19 | — | — | EP | disclosed |
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| EP-3087052-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-11-02 | — | — | EP | disclosed |
| WO-2015097091-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-02 | — | — | WO | disclosed |
| US-8822691-B2 | Pesticidal carboxamides | BAYER CROPSCIENCE AG (DE) | 2014-09-02 | — | — | US | disclosed |
| US-20120277185-A1 | Pesticidal Carboxamides | BAYER CROPSCIENDE AG (DE) | 2012-11-01 | — | — | US | disclosed |
| EP-1418171-B1 | Verfahren zur Herstellung von Perfluoroalkylanilins | SALTIGO GMBH (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-7041852-B2 | Perfluoroalkylanilines | BAYER CHEMICALS AG (DE) | 2006-05-09 | — | — | US | disclosed |
| US-20040152898-A1 | Perfluoroalkylanilines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-05 | — | — | US | disclosed |
| EP-1418171-A1 | Perfluoroalkylanilins | Bayer Chemicals AG (DE) | 2004-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277185-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | KIF11 4452/4885MAOB 1895/4885MAPT 4650/4885 |
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | ACHE, NIT2, CHRM1 | KIF11 3179/4885MAOB 422/4885MAPT 4303/4885 |
| US-20040152898-A1 | Perfluoroalkylanilines | PFAS, AFF2, AFF4 | KIF11 788/4885MAOB 949/4885MAPT 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.