Sugi Predict

Sugi Predict / Compounds / SCHEMBL297801

SCHEMBL297801

SCHEMBL297801

Nc1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 3/20 0.54
▸ MAPT P10636 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ MAOB P27338 3/20 0.44
▸ ALDH1A1 P00352 5/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ PTGS1 P23219 2/20 0.38
▸ CYP3A4 P08684 2/20 0.38
▸ TP53 P04637 1/20 0.38
▸ MAPK1 P28482 3/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ TSHR P16473 2/20 0.36
▸ GLA P06280 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ ALOX15 P16050 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5844932 0.87 KIF11 (0.48) KIF11MAPTMEN1KMT2AMAOB
SCHEMBL289976 0.87 KIF11 (0.48) KIF11MAPTMEN1KMT2AMAOB
SCHEMBL6900832 0.87 KIF11 (0.48) KIF11MAPTMEN1KMT2AMAOB
SCHEMBL19309077 0.85 KIF11 (0.46) KIF11MAPTMEN1KMT2AMAOB
SCHEMBL18355972 0.85 KIF11 (0.46) KIF11MAPTMEN1KMT2AMAOB
SCHEMBL22212787 0.85 KIF11 (0.46) KIF11MAPTMEN1KMT2AMAOB
SCHEMBL497772 0.85 ESR1 (0.41) KIF11MAPTALDH1A1TSHRGAA
SCHEMBL16207357 0.82 KIF11 (0.43) KIF11MAPTMEN1KMT2AMAOB
Propane SCHEMBL28874741 0.80 KIF11 (0.42) KIF11MAPTMEN1KMT2AMAOB
SCHEMBL445852 0.78 KIF11 (0.54) KIF11MAPTMEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110961151-B Ruthenium-copper bimetallic catalyst, preparation method and application thereof 扬州大学 2022-08-12 — — CN claimed
CN-110961151-A Ruthenium-copper bimetallic catalyst, preparation method and application thereof 扬州大学 2020-04-07 — — CN claimed
CN-101878192-B Method for producing 4-perfluoroisopropylaniline CENTRAL GLASS CO LTD 2014-03-05 — — CN claimed
CN-101878192-A Method for producing 4-perfluoroisopropylaniline CENTRAL GLASS CO LTD 2010-11-03 — — CN claimed
US-12540117-B2 Aniline compound used as RORγ regulator SHANGHAI LITEDD CO., LTD. (CN) 2026-02-03 — — US disclosed
EP-4151626-B1 ANILINE COMPOUND USED AS RORY REGULATOR LITTDD MEDICINES LTD (CN) 2025-04-09 — — EP disclosed
CN-115894442-B Substituted benzamide derivative or salt and composition acceptable by pesticides and application thereof 海利尔药业集团股份有限公司 2025-02-14 — — CN disclosed
CN-115724768-B Bisamide compound and preparation method and application thereof 广西思钺生物科技有限责任公司 2024-10-29 — — CN disclosed
CN-118580188-A Can be used as ROR gamma regulator aniline compound (B) 励缔(杭州)医药科技有限公司 2024-09-03 — — CN disclosed
US-20240287081-A1 PERFLUOROALKANE SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDIN AND PYRROLO[2,3-D]PYRIMIDIN COMPOUNDS AND USES THEREOF ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI 2024-08-29 — — US disclosed
CN-114436955-B Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof 复旦大学 2024-08-09 — — CN disclosed
CN-115872904-B N-hydroxy-N-phenyl aromatic amide derivative and application thereof 沈阳中化农药化工研发有限公司 2024-06-25 — — CN disclosed
US-6600074-B2 Useful as intermediates or raw materials for the synthesis of agricultural chemicals, pharmaceuticals NIHON NOHYAKU CO., LTD. (JP) 2003-07-29 — — US disclosed
EP-1301484-A2 CAPSAICIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 2003-04-16 — — EP disclosed
US-20020198399-A1 Perfluoroalkylated aniline compound and process for producing the same NIHON NOHYAKU CO., LTD. (JP) 2002-12-26 — — US disclosed
EP-1253128-A1 PERFLUOROISOPROPYLBENZENE DERIVATIVES Nihon Nohyaku Co., Ltd. (JP) 2002-10-30 — — EP disclosed
US-20020132853-A1 Capsaicin receptor ligands NEUROGEN CORPORATION 2002-09-19 — — US disclosed
WO-2002008221-A2 CAPSAICIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 2002-01-31 — — WO disclosed
JP-2001122836-A ANILINE DERIVATIVE AND METHOD FOR PRODUCING THE ANILINE NIPPON NOHYAKU CO LTD 2001-05-08 — — JP disclosed
EP-1006102-A2 Aniline derivative and process for producing the same NIHON NOHYAKU CO., LTD. (JP) 2000-06-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540117-B2 Aniline compound used as RORγ regulator RORA, RORB, RORC KIF11 3028/4885MAPT 1751/4885MEN1 4594/4885
US-20020132853-A1 Capsaicin receptor ligands TRPV1, TRPV5, TRPV2 KIF11 4138/4885MAPT 3250/4885MEN1 4876/4885
US-20020198399-A1 Perfluoroalkylated aniline compound and process for producing the same CYP8B1, CCR8, AFF1 KIF11 412/4885MAPT 3519/4885MEN1 4717/4885
US-20240287081-A1 PERFLUOROALKANE SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDIN AND PYRROLO[2,3-D]PYRIMIDIN COMPOUNDS AND USES THEREOF PPARD, PFAS, FOLR2 KIF11 2089/4885MAPT 3909/4885MEN1 3086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.