Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000095 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL2053138 | 0.79 | LMNA (0.52) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL15369533 | 0.79 | KMT2A (0.74) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL754132 | 0.77 | CYP2C19 (0.58) | ALDH1A1HPGDLMNATSHRMAPK1 | |
| SCHEMBL4769362 | 0.76 | LMNA (0.47) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL18860744 | 0.76 | TSHR (0.66) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL11190983 | 0.75 | SMN1; SMN2 (0.62) | ALDH1A1HSD17B10HPGDLMNAMAPK1 | |
| SCHEMBL27557939 | 0.75 | MMP8 (0.50) | LMNAMAPK1SMN1; SMN2KMT2A | |
| Formic Acid SCHEMBL28872029 | 0.74 | LMNA (0.46) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL5843726 | 0.74 | MDM4 (0.53) | KDM4EALDH1A1HPGDLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |