SCHEMBL754132

SCHEMBL754132

CC(=O)Nc1ccccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 4/20 0.58
POLB P06746 2/20 0.58
RAB9A P51151 4/20 0.53
NPC1 O15118 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
LMNA P02545 4/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
HPGD P15428 3/20 0.47
ALDH1A1 P00352 2/20 0.47
BRD4 O60885 1/20 0.44
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CYP1A2 P05177 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16568666 0.88 POLB (0.49) CYP2C19POLBRAB9ANPC1SMN1; SMN2
SCHEMBL2053138 0.87 LMNA (0.52) CYP2C19POLBLMNACES2CES1
SCHEMBL6438569 0.85 HPGD (0.47) CYP2C19POLBRAB9ANPC1SMN1; SMN2
SCHEMBL5843726 0.84 MDM4 (0.53) CYP2C19POLBRAB9ASMN1; SMN2LMNA
SCHEMBL1395462 0.83 LMNA (0.52) POLBLMNACES2CES1HPGD
SCHEMBL5483965 0.81 LMNA (0.53) LMNACES2CES1HPGDALDH1A1
SCHEMBL7326944 0.81 LMNA (0.53) LMNACES2CES1HPGDALDH1A1
SCHEMBL16430980 0.81 CYP2C19 (0.59) CYP2C19POLBRAB9ANPC1SMN1; SMN2
Formic Acid SCHEMBL28872029 0.81 LMNA (0.46) CYP2C19POLBLMNACES2CES1
SCHEMBL6447139 0.80 TGM2 (0.47) SMN1; SMN2LMNACES2CES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118090990-A Preparation method of stable isotope labeled hypnone internal standard reagent 谱同生物医药科技(常州)有限公司 2024-05-28 CN disclosed
US-20240115593-A1 METHISOPRINOL COMPOSITIONS PATEL REENA (IN) 2024-04-11 US disclosed
US-20210332120-A1 TRISPECIFIC ANTIBODIES AGAINST IL-17A, IL-17F AND OTHER PRO-INFLAMMATORY MOLECULE JOINT STOCK COMPANY "BIOCAD" (RU) 2021-10-28 US disclosed
US-11136408-B2 Anti-PD-1 antibodies, method for producing same and method for using same CLOSED JOINT-STOCK COMPANY "BIOCAD" (RU) 2021-10-05 US disclosed
US-10450376-B2 Anti-MET antibodies and compositions SYMPHOGEN A/S (DK) 2019-10-22 US disclosed
EP-3194444-B1 ANTI-MET ANTIBODIES AND COMPOSITIONS SYMPHOGEN AS (DK) 2019-07-10 EP disclosed
EP-3486257-A1 ANTI-PD-1 ANTIBODIES, METHOD FOR PRODUCING SAME AND METHOD FOR USING SAME Joint Stock Company "Biocad" (RU) 2019-05-22 EP disclosed
US-20190127478-A1 ANTI-PD-1 ANTIBODIES, METHOD FOR PRODUCING SAME AND METHOD FOR USING SAME CLOSED JOINT-STOCK COMPANY "BIOCAD" (RU) 2019-05-02 US disclosed
EP-3431501-A1 ANTI NOTCH-1 ANTIBODIES Pfizer Inc (US) 2019-01-23 EP disclosed
CN-109071956-A Composition for thermoplastic elastomer and its manufacturing method and elastomer molded body JXTG能源株式会社 2018-12-21 CN disclosed
EP-1291714-A1 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-12 EP disclosed
US-6451516-B1 AMINOPYRIDINIUM DYE WITH METHIN LINKAGE TERMINATED BY A HETEROCVYCLIC NUCLEUS AS FOUND IN CYANINE DYES EASTMAN KODAK COMPANY 2002-09-17 US disclosed
WO-2002011900-A1 EXPANDABLE GRAPHITE AND METHOD GRAFTECH INC. (US) 2002-02-14 WO disclosed
EP-0814374-A2 Stabilized heat-sensitive imaging material LABELON CORPORATION (US) 1997-12-29 EP disclosed
US-5672560-A PHOSPHATE LABELON CORPORATION (US) 1997-09-30 US disclosed
EP-0679264-A4 1995-11-29 EP disclosed
EP-0679264-A1 THERMAL IMAGING MATERIAL AND PREPARATION LABELON CORPORATION (US) 1995-11-02 EP disclosed
US-5424182-A Mixture of a silver salt of an organic acid, reducing agents, toner and carrier LABELON CORPORATION (US) 1995-06-13 US disclosed
WO-1994016361-A1 THERMAL IMAGING MATERIAL AND PREPARATION LABELON CORPORATION (US) 1994-07-21 WO disclosed
US-4272106-A TRANSPARENT DYE LAYER WHICH CAN UNDERGO COLOR SHIFT IN RESPONSE TO DEVELOPER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115593-A1 METHISOPRINOL COMPOSITIONS INMT, MIF, CHRM1 CYP2C19 992/4885POLB 3121/4885RAB9A 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.