Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395462 | 0.82 | LMNA (0.52) | LMNACES2CES1MAPK1FABP4 | |
| SCHEMBL6443998 | 0.81 | MAPT (0.44) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL5483965 | 0.80 | LMNA (0.53) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL7326944 | 0.80 | LMNA (0.53) | LMNACES2CES1MAPK1NAAA | |
| SCHEMBL754132 | 0.79 | CYP2C19 (0.58) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL2053138 | 0.79 | LMNA (0.52) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL184136 | 0.78 | ALDH1A1 (0.62) | LMNAFABP4KDM4EALDH1A1HPGD | |
| SCHEMBL5928515 | 0.77 | ALDH1A1 (0.62) | LMNACES2CES1KDM4EALDH1A1 | |
| SCHEMBL5843726 | 0.77 | MDM4 (0.53) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL390944 | 0.77 | LMNA (0.53) | LMNACES2CES1MAPK1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007834-A1 | SULPHONIUM SALT INITIATORS | Ciba Holding Inc. (CH) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118794-A1 | SULPHONIUM SALT INITIATORS | CIBA HOLDING INC. (CH) | 2007-10-25 | — | — | WO | disclosed |