Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 6/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.40 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5843296 | 0.98 | HRH2 (0.49) | HRH2HRH1DRD3LMNAPOLB | |
| SCHEMBL27911992 | 0.83 | ALDH1A1 (0.47) | HRH2HRH1LMNAPOLBTSHR | |
| SCHEMBL12120100 | 0.81 | ALDH1A1 (0.49) | HRH2HRH1LMNAPOLBTSHR | |
| SCHEMBL24745090 | 0.81 | CHRNB2 (0.48) | HRH2HRH1LMNAPOLBALDH1A1 | |
| SCHEMBL501897 | 0.79 | ALDH1A1 (0.58) | LMNAPOLBTSHRALDH1A1L3MBTL1 | |
| SCHEMBL12424660 | 0.78 | TSHR (0.54) | HRH2HRH1LMNAPOLBTSHR | |
| SCHEMBL12550647 | 0.77 | ALDH1A1 (0.38) | HRH2HRH1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5844774 | 0.77 | ALDH1A1 (0.60) | LMNAPOLBTSHRALDH1A1L3MBTL1 | |
| SCHEMBL14394504 | 0.77 | HRH2 (0.44) | HRH2HRH1DRD3LMNATSHR | |
| SCHEMBL17557992 | 0.77 | HRH2 (0.47) | HRH2HRH1DRD3LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2004-07-01 | — | — | US | claimed |
| US-6664394-B2 | As inactivator of antigen- specific T cells is useful in the prophylaxis or therapy of autoimmune diseases, disorders involving an autoimmune component or neoplastic diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-12-16 | — | — | US | claimed |
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2002-10-03 | — | — | US | claimed |
| WO-2000073257-A1 | DERIVATIVES OF BUTYRIC ACID AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2000-12-07 | — | — | WO | claimed |
| US-7034020-B2 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCE (US) | 2006-04-25 | — | — | US | disclosed |
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2004-07-01 | — | — | US | disclosed |
| US-6664394-B2 | As inactivator of antigen- specific T cells is useful in the prophylaxis or therapy of autoimmune diseases, disorders involving an autoimmune component or neoplastic diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-12-16 | — | — | US | disclosed |
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2002-10-03 | — | — | US | disclosed |
| US-6407107-B1 | 4-(MORPHOLINO)ALKYL BUTANAMIDE DERIVATIVES; AUTOIMMUNE DISEASES; ANTICARCINOGENIC AGENTS | THE BOARD OF TRUSTEES OF THE UNVERSITY OF ARKANSAS | 2002-06-18 | — | — | US | disclosed |
| WO-2000073257-A1 | DERIVATIVES OF BUTYRIC ACID AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | CD4, NFATC1, GABRA4 | HRH2 818/4885HRH1 525/4885DRD3 1791/4885 |
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | CD4, NFATC1, GABRA4 | HRH2 810/4885HRH1 516/4885DRD3 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.