Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GYS1 | P13807 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048208 | 0.85 | GLA (0.35) | HSD17B10USP7GAAALOX15POLB | |
| Water SCHEMBL28777074 | 0.81 | HSD17B10 (0.43) | HSD17B10ALDH1A1HPGDUSP7SMARCA2 | |
| SCHEMBL28431087 | 0.81 | GYS1 (0.47) | HSD17B10ALDH1A1GYS1BACE1ALOX5 | |
| SCHEMBL27771054 | 0.81 | HSD17B10 (0.43) | HSD17B10ALDH1A1HPGDSMARCA2SMARCA4 | |
| SCHEMBL29723384 | 0.80 | BACE1 (0.39) | HSD17B10ALDH1A1GYS1BACE1ALOX5 | |
| Water SCHEMBL28272876 | 0.80 | HSD17B10 (0.42) | HSD17B10ALDH1A1HPGDSMARCA2SMARCA4 | |
| SCHEMBL7463846 | 0.79 | CYP3A4 (0.52) | HSD17B10GYS1USP7BRD4KIF11 | |
| SCHEMBL27724771 | 0.79 | ALDH1A1 (0.41) | HSD17B10ALDH1A1BACE1HPGDSMARCA2 | |
| SCHEMBL27707899 | 0.79 | ALDH1A1 (0.41) | HSD17B10ALDH1A1HPGDKIF11KDM4E | |
| SCHEMBL8733742 | 0.79 | ESR2 (0.46) | HSD17B10ALDH1A1GYS1BACE1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | claimed |
| CN-115124485-B | Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-115124485-A | Benzoxazole derivatives containing sulfoxide as well as preparation method and application thereof | 中国医学科学院药物研究所 | 2022-09-30 | — | — | CN | disclosed |