Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19765559 | 0.85 | ALDH1A1 (0.39) | ELANEALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL28431087 | 0.81 | GYS1 (0.47) | ESR2BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL29723384 | 0.80 | BACE1 (0.39) | ESR2BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL5845451 | 0.79 | HSD17B10 (0.41) | ESR2BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL27727564 | 0.79 | BACE1 (0.42) | ESR2BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL10617137 | 0.77 | ESR2 (0.55) | ESR2ELANEBACE1ALOX5ALDH1A1 | |
| SCHEMBL5934445 | 0.76 | HNF4A (0.54) | PTPN1 | |
| SCHEMBL24252550 | 0.76 | HSD11B1 (0.40) | ESR2ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL790518 | 0.76 | ESR2 (0.50) | ESR2ELANEBACE1ALOX5ALDH1A1 | |
| SCHEMBL29391919 | 0.76 | HSD11B1 (0.40) | ESR2ALDH1A1HPGDBCL2L1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877607-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1998-11-18 | — | — | EP | claimed |
| WO-1997027846-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1997-08-07 | — | — | WO | claimed |