Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | CA12 | O43570 | 3/20 | 0.70 |
| ▸ | CA1 | P00915 | 3/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.70 |
| ▸ | CA3 | P07451 | 3/20 | 0.70 |
| ▸ | CA4 | P22748 | 3/20 | 0.70 |
| ▸ | CA6 | P23280 | 3/20 | 0.70 |
| ▸ | CA5A | P35218 | 3/20 | 0.70 |
| ▸ | CA7 | P43166 | 3/20 | 0.70 |
| ▸ | CA9 | Q16790 | 3/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.70 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.70 |
| ▸ | DPP4 | P27487 | 3/20 | 0.70 |
| ▸ | BACE1 | P56817 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471934 | 1.00 | KDM4E (0.70) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL27524817 | 0.98 | KDM4E (0.68) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL27524820 | 0.98 | KDM4E (0.68) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL15481424 | 0.87 | BACE1 (0.66) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL12220501 | 0.85 | IAPP (0.73) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL14472602 | 0.85 | KDM4E (0.70) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL584596 | 0.85 | KDM4E (0.58) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL111230 | 0.85 | KDM4E (0.58) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL8965107 | 0.84 | BACE1 (0.88) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL8965104 | 0.84 | BACE1 (0.88) | KDM4EHSD17B10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025081932-A1 | RETINOL DERIVATIVE OR SALT THEREOF, AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳市护家科技有限公司 | 2025-04-24 | — | — | WO | claimed |
| CN-119841755-A | Retinol derivative or its salt, and preparation method and application thereof | 深圳市护家科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-121570519-A | Peony polyphenol extract and preparation method and application thereof | 江苏省中国科学院植物研究所 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025081932-A1 | RETINOL DERIVATIVE OR SALT THEREOF, AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳市护家科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| CN-119841755-A | Retinol derivative or its salt, and preparation method and application thereof | 深圳市护家科技有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-118266572-A | Application of 3-methoxyphenyl-2-acrylic compound as bitter taste inhibitor | 华南理工大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-111602087-B | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, polymer and compound | JSR株式会社 | 2023-03-24 | — | — | CN | disclosed |
| CN-113880695-A | Preparation method of 4-vinylphenol compound | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-01-04 | — | — | CN | disclosed |
| CN-111602087-A | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, polymer and compound | JSR株式会社 | 2020-08-28 | — | — | CN | disclosed |
| CN-110938582-A | Culture medium capable of improving cell proliferation activity and preparation method thereof | 南京晓庄学院 | 2020-03-31 | — | — | CN | disclosed |
| WO-2019202884-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL ELEMENT, POLYMER, AND COMPOUND | JSR株式会社 | 2019-10-24 | — | — | WO | disclosed |
| EP-2528897-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-12-05 | — | — | EP | disclosed |
| US-20120283242-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-11-08 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2412701-A1 | NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT | Ajinomoto Co., Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| WO-2011093524-A9 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-12-01 | — | — | WO | disclosed |
| US-7053071-B2 | For therapy of leukemia or other forms of cancer or for treating disease conditions caused by apoptosis of cells | THE BURNHAM INSTITUTE (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1456165-A1 | INDUCTION OF APOPTOSIS IN CANCER CELLS | The Burnham Institute (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20030176506-A1 | Induction of apoptosis in cancer cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH | 2003-09-18 | — | — | US | disclosed |
| WO-2003048101-A1 | INDUCTION OF APOPTOSIS IN CANCER CELLS | THE BURNHAM INSTITUTE (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | KDM4E 1343/4885HSD17B10 1491/4885CA12 1671/4885 |
| US-20030176506-A1 | Induction of apoptosis in cancer cells | MCL1, BAD, BCL2 | KDM4E 2860/4885HSD17B10 2109/4885CA12 2413/4885 |
| US-20120283242-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | TPD52L2, CCNE2, CDK2 | KDM4E 719/4885HSD17B10 1944/4885CA12 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.