Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232154 | 0.84 | ERN1 (0.43) | ERN1ALDH1A1TSHRKCNJ1TDP1 | |
| SCHEMBL6438818 | 0.82 | ALDH1A1 (0.43) | ERN1ALDH1A1TSHRKCNJ1TDP1 | |
| SCHEMBL4293546 | 0.82 | ERN1 (0.42) | ERN1ALDH1A1TSHRKCNJ1TDP1 | |
| SCHEMBL13743324 | 0.78 | TSHR (0.36) | ERN1ALDH1A1TSHRKCNJ1TDP1 | |
| SCHEMBL19862054 | 0.78 | ALDH1A1 (0.35) | ERN1ALDH1A1TSHRKCNJ1TDP1 | |
| SCHEMBL12593983 | 0.78 | ERN1 (0.40) | ERN1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5643995 | 0.78 | ERN1 (0.59) | ERN1 | |
| SCHEMBL16415856 | 0.78 | ERN1 (0.39) | ERN1ALDH1A1TSHRKCNJ1TDP1 | |
| SCHEMBL21121085 | 0.78 | TDP1 (0.42) | ERN1ALDH1A1TSHRKCNJ1TDP1 | |
| SCHEMBL31104367 | 0.78 | ALDH1A1 (0.35) | ERN1ALDH1A1TSHRKCNJ1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514873-B1 | Process for oxidation of organic substrates and catalyst compositions for performing the same | EVONIK DEGUSSA GMBH (DE) | 2008-03-19 | — | — | EP | claimed |
| EP-1514873-A1 | Process for oxidation of organic substrates and catalyst compositions for performing the same | Degussa AG (DE) | 2005-03-16 | — | — | EP | claimed |
| CN-117881669-A | Condensed ring heteroaryl compounds and uses thereof | 比西切姆有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4232444-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-108101930-B | Micromolecule receptor material containing benzothiadiazolothiophene unit and preparation method and application thereof | 武汉大学 | 2020-10-30 | — | — | CN | disclosed |
| EP-3224237-A1 | NECROSIS INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2017-10-04 | — | — | EP | disclosed |
| WO-2016101885-A1 | NECROSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2016-06-30 | — | — | WO | disclosed |
| US-8188082-B2 | 5,6,7,8-tetrahydro-imidazo[1,5-α]pyrazine derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-05-29 | — | — | US | disclosed |
| EP-2125823-B1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |
| US-20030181552-A1 | Polymer additive compositions and articles comprising novel fluorinated and alkylated alditol derivatives | ANDERSON JOHN D (US) | 2003-09-25 | — | — | US | disclosed |
| US-20030171462-A1 | Polyolefin compositions and articles comprising novel fluorinated and alkylated alditol derivatives | ANDERSON JOHN D (US) | 2003-09-11 | — | — | US | disclosed |
| US-20030139612-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | ANDERSON JOHN D (US) | 2003-07-24 | — | — | US | disclosed |
| EP-1313741-A2 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | Milliken & Company (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6548581-B2 | Radiation transparent polyolefin | MILLIKEN & COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-20030013786-A1 | Novel asymmetric halogen-alkyl alditol derivatives as nucleators and clarifiers for polyolefins, and polyolefin plastic compositions containing same | MILLIKEN & COMPANY | 2003-01-16 | — | — | US | disclosed |
| WO-2002076385-A2 | ASYMMETRIC BENZALDEHYDE ALDITOL DERIVATIVES, METHODS OF MAKING THEREOF, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | MILLIKEN & COMPANY (US) | 2002-10-03 | — | — | WO | disclosed |
| US-20020062034-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | MILLIKEN &COMPANY | 2002-05-23 | — | — | US | disclosed |
| WO-2002020528-A2 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | MILLIKEN & COMPANY (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139612-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | ALDOA, SORD, ADH1A | ERN1 2389/4885ALDH1A1 107/4885TSHR 4515/4885 |
| US-20020062034-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | ALDOA, SORD, DERA | ERN1 2583/4885ALDH1A1 110/4885TSHR 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.