SCHEMBL584641

SCHEMBL584641

C=CC(=O)OC(CC)C([SiH3])(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.36
HPGD P15428 1/20 0.35
THRB P10828 2/20 0.33
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28360932 0.86 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28916320 0.84 TSHR (0.35) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28446056 0.80 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL28505942 0.79 KCNH2 (0.37) TSHRALDH1A1SMN1; SMN2HSD17B10
SCHEMBL3478326 0.79 TSHR (0.32) TSHRHPGD
SCHEMBL584058 0.77 ALDH1A1 (0.38) TSHRTHRBALDH1A1
SCHEMBL6782736 0.77 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL17300322 0.76 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28170370 0.75 THRB (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL109234 0.75 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3929260-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2025-12-17 EP disclosed
EP-4011978-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2025-11-19 EP disclosed
EP-4624479-A1 HYDROSILANE COMPOSITION AND METHOD FOR PREPARING HYDROSILYLATION PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-10-01 EP disclosed
WO-2025095375-A1 METHOD FOR PREPARING NON-FLUORINE-BASED SILOXANE-POLYMER COMPOSITE BINDER, NON-FLUORINE-BASED SILOXANE-POLYMER COMPOSITE BINDER PREPARED USING SAME, AND ELECTRODE COMPRISING SAME 한국전기연구원 2025-05-08 WO disclosed
US-20250115718-A1 Dual Cure Compositions SAINT GOBAIN PERFORMANCE PLASTICS CORP (US) 2025-04-10 US disclosed
WO-2025053278-A1 ORGANOPOLYSILOXANE, ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, ORGANOPOLYSILOXANE FOR NEAR-INFRARED OPTICAL WAVEGUIDE, ORGANOPOLYSILOXANE COMPOSITION FOR NEAR-INFRARED OPTICAL WAVEGUIDE, CURED PRODUCT FOR NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL TRANSMISSION MEMBER, AND NEAR-INFRARED OPTICAL WAVEGUIDE PRODUCTION METHOD 三菱ケミカル株式会社 2025-03-13 WO disclosed
WO-2025053279-A1 ORGANOPOLYSILOXANE, ORGANOPOLYSILOXANE-CONTAINING RESIN COMPOSITION, CURED PRODUCT THEREOF, ORGANOPOLYSILOXANE FOR NEAR-INFRARED OPTICAL WAVEGUIDE, ORGANOPOLYSILOXANE-CONTAINING RESIN COMPOSITION FOR NEAR-INFRARED OPTICAL WAVEGUIDE, CURED PRODUCT FOR NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL TRANSMISSION MEMBER, AND NEAR-INFRARED OPTICAL WAVEGUIDE PRODUCTION METHOD 三菱ケミカル株式会社 2025-03-13 WO disclosed
WO-2025053280-A1 OPTICAL WAVEGUIDE AND OPTICAL MEMBER HAVING OPTICAL WAVEGUIDE 三菱ケミカル株式会社 2025-03-13 WO disclosed
US-12221563-B2 Curable composition KANEKA CORPORATION (JP) 2025-02-11 US disclosed
US-20250019536-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2025-01-16 US disclosed
EP-1832613-B1 GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER KANEKA CORP (JP) 2012-02-15 EP disclosed
EP-1964856-B1 POLYMER PARTICLES, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE PARTICLES, AND MOLDINGS KANEKA CORP (JP) 2011-05-25 EP disclosed
US-20090109538-A1 Polymer Particles, Process for Production Thereof, Resin Compositions Containing the Particles, and Moldings KANEKA CORPORATION (JP) 2009-04-30 US disclosed
EP-1964856-A1 POLYMER PARTICLES, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE PARTICLES, AND MOLDINGS Kaneka Corporation (JP) 2008-09-03 EP disclosed
US-20080085975-A1 Graft Copolymer, Method For Producing The Same And Resin Composition Containing The Graft Copolymer KANEKA CORPORATION (JP) 2008-04-10 US disclosed
EP-1832613-A1 GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER Kaneka Corporation (JP) 2007-09-12 EP disclosed
EP-1394217-A2 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
EP-1394209-A1 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
US-5196260-A Polysiloxanes with vinyl groups copolymerized with vinyl monomer, washfastness, whiteness CIBA-GEIGY CORPORATION (US) 1993-03-23 US disclosed
EP-0212350-B1 SILICON-CONTAINING ADDITION INTERPOLYMERS FROM ISOBORNYL (METH)ACRYLATE AND COATING METHOD PPG INDUSTRIES, INC. (US) 1990-10-24 EP disclosed