Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253556 | 0.88 | LMNA (0.43) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL11296811 | 0.82 | KDM4E (0.41) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL76276 | 0.77 | KDM4E (0.53) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL30337840 | 0.76 | NPC1 (0.69) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL7857203 | 0.76 | NPC1 (0.69) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL28214707 | 0.74 | PDE6D (0.39) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL29871080 | 0.73 | NPC1 (0.55) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL15707564 | 0.73 | NPC1 (0.56) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL45835 | 0.73 | NPC1 (0.54) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL28037090 | 0.72 | NPC1 (0.39) | NPC1RAB9ALMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074853-B2 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| US-6861458-B2 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION (US) | 2005-03-01 | — | — | US | disclosed |
| US-20050014951-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2005-01-20 | — | — | US | disclosed |
| US-6803395-B2 | POLYSILOXANE HAVING THEREON A HYDROPHILIC MOIETY AND A LIGHTFASTNESS MOIETY | XEROX CORPORATION | 2004-10-12 | — | — | US | disclosed |
| US-20030137570-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-24 | — | — | US | disclosed |
| US-20030133886-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-17 | — | — | US | disclosed |
| US-6569511-B1 | Polysiloxane having a hydrophilic moiety and a lightfastness moiety; ink jet coating | XEROX CORPORATION | 2003-05-27 | — | — | US | disclosed |
| WO-2003029227-A1 | ADHESION PROMOTERS CONTAINING BENZOTRIAZOLES | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014951-A1 | Photoprotective and lightfastness-enhancing siloxanes | LRRFIP1, LRRC59, MMS19 | NPC1 4542/4885RAB9A 940/4885LMNA 396/4885 |
| US-20030133886-A1 | Photoprotective and lightfastness-enhancing siloxanes | ITGA1, ITGB1, ITGB8 | NPC1 4021/4885RAB9A 1019/4885LMNA 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.