Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584692 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1MAPTMAPK1 | |
| SCHEMBL3972652 | 0.87 | MAPT (0.51) | ALDH1A1TSHRTDP1MAPTMAPK1 | |
| SCHEMBL3972651 | 0.87 | MAPT (0.51) | ALDH1A1TSHRTDP1MAPTMAPK1 | |
| SCHEMBL585142 | 0.86 | HCAR3 (0.47) | ALDH1A1TSHRTDP1MAPTMAPK1 | |
| SCHEMBL585141 | 0.86 | HCAR3 (0.47) | ALDH1A1TSHRTDP1MAPTMAPK1 | |
| SCHEMBL584659 | 0.83 | PTGER4 (0.45) | ALDH1A1MAPTHTTPTGER4 | |
| SCHEMBL4966167 | 0.82 | MAPT (0.44) | ALDH1A1TSHRTDP1MAPTMAPK1 | |
| SCHEMBL3915803 | 0.80 | MAPT (0.43) | ALDH1A1MAPTMAPK1HCAR3L3MBTL1 | |
| SCHEMBL3915802 | 0.80 | MAPT (0.43) | ALDH1A1MAPTMAPK1HCAR3L3MBTL1 | |
| SCHEMBL4967065 | 0.80 | MAPT (0.48) | ALDH1A1TSHRTDP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797077-B1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF I | ASTRAZENECA AB (SE) | 2012-02-15 | — | — | EP | disclosed |