Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847222 | 0.83 | MEN1 (0.34) | ALDH1A1MAPTMAPK1LMNAKDM4E | |
| SCHEMBL4345452 | 0.78 | PRKCA (0.61) | ALDH1A1MAPTMAPK1PRKCAPRKCE | |
| SCHEMBL4343073 | 0.78 | PRKCA (0.61) | ALDH1A1MAPTMAPK1PRKCAPRKCE | |
| SCHEMBL4345443 | 0.78 | PRKCA (0.61) | ALDH1A1MAPTMAPK1PRKCAPRKCE | |
| SCHEMBL4337617 | 0.78 | PRKCA (0.61) | ALDH1A1MAPTMAPK1PRKCAPRKCE | |
| SCHEMBL7527477 | 0.77 | MAPT (0.41) | ALDH1A1MAPTMAPK1LMNAPRKCA | |
| SCHEMBL7155099 | 0.77 | MAPT (0.41) | ALDH1A1MAPTMAPK1LMNAPRKCA | |
| SCHEMBL6810153 | 0.77 | MAPT (0.41) | ALDH1A1MAPTMAPK1LMNAPRKCA | |
| SCHEMBL6203333 | 0.76 | MAPT (0.40) | ALDH1A1MAPTMAPK1LMNAPRKCA | |
| SCHEMBL5606421 | 0.76 | MAPT (0.40) | ALDH1A1MAPTMAPK1LMNAPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | claimed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | claimed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | claimed |
| US-6992044-B1 | Substituted phenyluracils | BAYER CROPSCIENCE AG (DE) | 2006-01-31 | — | — | US | disclosed |
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | ALDH1A1 44/4885MAPT 2988/4885MAPK1 2666/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | ALDH1A1 44/4885MAPT 2988/4885MAPK1 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.