Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848180 | 0.90 | CDK1 (0.58) | CDK1GAACYP1A2MEN1USP2 | |
| SCHEMBL8106622 | 0.87 | GAA (0.58) | CDK1GAACYP1A2MEN1USP2 | |
| SCHEMBL10395502 | 0.85 | CDK1 (0.56) | CDK1GAACYP1A2MEN1KMT2A | |
| SCHEMBL11385667 | 0.84 | CDK1 (0.57) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL14601840 | 0.84 | CDK1 (0.45) | CDK1GAA | |
| SCHEMBL8507050 | 0.83 | CDK1 (0.56) | CDK1GAACYP1A2MEN1KMT2A | |
| SCHEMBL5847781 | 0.82 | CDK1 (0.61) | CDK1GAACYP1A2MEN1KMT2A | |
| SCHEMBL1405765 | 0.82 | GAA (0.59) | CDK1GAACYP1A2MEN1KMT2A | |
| SCHEMBL9814877 | 0.81 | CDK1 (0.55) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL8011325 | 0.81 | CDK1 (0.43) | CDK1GAAMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141531-B2 | For protecting crop plants from phytotoxic side effects of herbicides | HOECHST SCHERING AGREVO GMBH (DE) | 2006-11-28 | — | — | US | claimed |
| US-20040157737-A1 | For protecting crop plants from phytotoxic side effects of herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-08-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157737-A1 | For protecting crop plants from phytotoxic side effects of herbicides | GSTO1, CYP1A1, HAO2 | CDK1 2095/4885GAA 1201/4885CYP1A2 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.