SCHEMBL5848154

SCHEMBL5848154

Clc1c(Cl)c(Cl)c(Sc2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)c(Cl)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183963 0.78
SCHEMBL11637274 0.78
SCHEMBL224297 0.73 MEN1 (0.31) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL3292039 0.70
Perchlorobenzene SCHEMBL1330781 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL26562 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL8872243 0.67 ALDH1A1 (0.50) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL1953174 0.67
SCHEMBL11213956 0.67
SCHEMBL754914 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7148383-B2 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED (US) 2006-12-12 US disclosed
US-20050240060-A1 Low loss high refractive index vinyl sulfide compounds and method of making same LESLIE THOMAS M 2005-10-27 US disclosed
US-6933412-B2 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED (US) 2005-08-23 US disclosed
US-20040044251-A1 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED 2004-03-04 US disclosed
US-20040030093-A1 Metal catalyst for ring-opening polymerization of heterocyclic compound SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-02-12 US disclosed
EP-1340780-A1 METAL CATALYST FOR RING-OPENING POLYMERIZATION OF HETEROCYCLIC COMPOUND SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-03 EP disclosed
US-6558276-B1 Improved feeling without impairing intrinsic resilience; core made from rubber composition of a base rubber, an organic peroxide, an alpha, beta unsaturated carboxylic acid, and a bis type halogen-substituted phenyl disulfide SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2003-05-06 US disclosed
US-6241625-B1 A GOLF BALL COMPRISING A COVER MEMBER AND A CORE MEMBER, WHEREIN POLYAMIDE, TERPOLYMER IONOMER CONTAINING ETHYLENE, (METH)ACRYLIC ACID, AND (METH)ACRYLIC ESTER MIXTURES WITH PEROXIDE AND SULFIDE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-06-05 US disclosed
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240060-A1 Low loss high refractive index vinyl sulfide compounds and method of making same CRY2, SOS2, CRYZ MEN1 4251/4885ALDH1A1 1610/4885LMNA 4335/4885
US-20040044251-A1 Low loss high refractive index vinyl sulfide compounds and method of making same SOS2, CRY2, PER2 MEN1 4120/4885ALDH1A1 1568/4885LMNA 4476/4885
US-20040030093-A1 Metal catalyst for ring-opening polymerization of heterocyclic compound MAX, PCNA, POLM MEN1 830/4885ALDH1A1 2856/4885LMNA 884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.