SCHEMBL584824

SCHEMBL584824

CCc1c(CC)c2oc1cc2CC

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HSD17B3 P37058 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
MCL1 Q07820 1/20 0.30
TSHR P16473 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
PPARG P37231 1/20 0.30
HTT P42858 1/20 0.30
MAPK10 P53779 1/20 0.30
NCOA2 Q15596 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29498227 1.00 KDM4E (0.32) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL3421916 0.76 BACE1 (0.35) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL1667901 0.73 KDM4E (0.37) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL29368334 0.73 KDM4E (0.37) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL156003 0.70 GABRA1 (0.35) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL167880 0.69 HSD17B3 (0.36) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL8637400 0.65
SCHEMBL29368171 0.62 ALDH1A1 (0.35) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL156024 0.62 ALDH1A1 (0.35) KDM4EALDH1A1POLBHSD17B10HSD17B3
SCHEMBL168554 0.61 GRIN2D (0.36) POLBESR1ESR2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912868-B2 Conductive concentrated resin composition, conductive polyamide resin composition comprising conductive concentrated resin composition, method of preparing same and molded article LG CHEM, LTD. (KR) 2024-02-27 US claimed
CN-110114412-B Thermoplastic resin composition and molded article prepared therefrom 乐天尖端材料株式会社 2022-05-13 CN claimed
EP-2267078-B2 Polyphenylene ether thermoplastic resin composition, and molded product using the same LOTTE CHEMICAL CORP (KR) 2021-11-03 EP claimed
US-11091634-B2 Thermoplastic resin composition and molded product produced therefrom LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2021-08-17 US claimed
US-20200123378-A1 Thermoplastic Resin Composition and Molded Product Produced Therefrom LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2020-04-23 US claimed
WO-2020067673-A1 POLYAMIDE/POLYPHENYLENE ETHER RESIN COMPOSITION AND MOLDED PRODUCT USING SAME 롯데케미칼 주식회사 2020-04-02 WO claimed
EP-3564317-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED PRODUCT PRODUCED THEREFROM Lotte Advanced Materials Co., Ltd. (KR) 2019-11-06 EP claimed
US-20190016888-A1 Polyamide/Polyphenylene Ether Resin Composition, and Vehicle Molded Product Prepared Therefrom LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2019-01-17 US claimed
EP-3093853-B1 CONDUCTIVE POLYAMIDE/POLYPHENYLENE ETHER RESIN COMPOSITION AND AUTOMOTIVE MOLDED ARTICLE MANUFACTURED THEREFROM LOTTE ADVANCED MAT CO LTD (KR) 2018-10-17 EP claimed
EP-2267078-B1 Polyphenylene ether thermoplastic resin composition, and molded product using the same LOTTE ADVANCED MAT CO LTD (KR) 2018-01-24 EP claimed
EP-2497801-A1 POLYPHENYLENE-ETHER-BASED RESIN COMPOSITION, AND MOLDINGS USING SAME Cheil Industries Inc. (KR) 2012-09-12 EP claimed
US-20120214932-A1 Polyphenylene Ether-Based Resin Composition and Molded Product Using the Same CHEIL INDUSTRIES INC. (KR) 2012-08-23 US claimed
US-20110251313-A1 Phosphonate Compound and Flame Retardant Styrenic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2011-10-13 US claimed
US-20100327234-A1 Polyphenylene Ether Thermoplastic Resin Composition, Method of Preparing the Same, and Molded Product Using the Same CHEIL INDUSTRIES INC. (KR) 2010-12-30 US claimed
EP-2267078-A1 Polyphenylene ether thermoplastic resin composition, and molded product using the same Cheil Industries Inc. (KR) 2010-12-29 EP claimed
US-20080161453-A1 Polyphenylene Sulfide Resin Composition and Plastic Mold Produced Using the Same CHEIL INDUSTRIES INC. (KR) 2008-07-03 US claimed
JP-2007501308-A 2007-01-25 JP claimed
EP-1651718-A4 FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2006-09-20 EP claimed
EP-1651718-A1 FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION Cheil Industries Inc. (KR) 2006-05-03 EP claimed
WO-2005012418-A1 FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION CHEIL INDUSTRIES INC. (KR) 2005-02-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251313-A1 Phosphonate Compound and Flame Retardant Styrenic Resin Composition Including the Same PFN1, TAF1, REV1 KDM4E 2510/4885ALDH1A1 1864/4885POLB 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.