Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27003471 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL31573923 | 0.74 | MAOA (0.40) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL4931181 | 0.72 | CYP1A2 (0.55) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL29590196 | 0.72 | KDM4E (0.62) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL6778388 | 0.69 | CYP1A2 (0.50) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL27678258 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL27678257 | 0.67 | KDM4E (0.52) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL3277376 | 0.66 | GAA (0.49) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL29207958 | 0.66 | CYP1A2 (0.58) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL19776415 | 0.66 | ALDH1A1 (0.40) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7150967-B2 | Fluorescent tags for amino acid and nucleic acid analysis | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 2006-12-19 | — | — | US | disclosed |
| US-20040018517-A1 | Fluorescent tags for amino acid and nucleic acid analysis | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2004-01-29 | — | — | US | disclosed |
| EP-0810861-B1 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | UNIV NORTH CAROLINA (US) | 2002-06-05 | — | — | EP | disclosed |
| US-6319929-B1 | VIRAL DISEASES AND HIV TREATMENT | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2001-11-20 | — | — | US | disclosed |
| US-5847165-A | Suksdorfin analogs, compositions thereof, and methods for making and using thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0810861-A4 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | UNIV NORTH CAROLINA (US) | 1998-07-08 | — | — | EP | disclosed |
| US-5726204-A | RETROVIRUS INHIBITORS | BIOTECH RESEARCH LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0810861-A1 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | The University of North Carolina at Chapel Hill (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5637589-A | VIRICIDES; THERAPY FOR RETROVIRUS OR AIDS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-06-10 | — | — | US | disclosed |
| WO-1996025930-A1 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-08-29 | — | — | WO | disclosed |
| WO-1995029920-A1 | KHELLACTONE DERIVATIVES AND RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AND IMMUNOSTIMULATING AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018517-A1 | Fluorescent tags for amino acid and nucleic acid analysis | DNTT, DIMT1, NUDT1 | KDM4E 4562/4885ALDH1A1 488/4885HPGD 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.