Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596276 | 0.80 | LTB4R (0.30) | — | |
| SCHEMBL5845787 | 0.80 | LTB4R (0.30) | — | |
| SCHEMBL9298866 | 0.74 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL7176550 | 0.73 | OPRM1 (0.34) | OPRM1 | |
| SCHEMBL191884 | 0.68 | GRIN2D (0.41) | — | |
| SCHEMBL8517438 | 0.67 | OPRM1 (0.42) | OPRM1 | |
| SCHEMBL17928403 | 0.67 | ALDH1A1 (0.37) | MEN1KMT2A | |
| SCHEMBL10791429 | 0.65 | SLC22A2 (0.36) | — | |
| Adamantane SCHEMBL28970317 | 0.65 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL892134 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015223-B1 | Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2006-03-21 | — | — | US | disclosed |
| US-7015230-B1 | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2006-03-21 | — | — | US | disclosed |