Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63240 | 0.91 | — | — | |
| SCHEMBL29365040 | 0.91 | — | — | |
| SCHEMBL16582039 | 0.91 | MAPT (0.45) | MAPTHDAC8MEN1KMT2ACYP2A6 | |
| Ammonia Solution, Strong SCHEMBL4964195 | 0.87 | — | — | |
| SCHEMBL3320890 | 0.87 | MAPT (0.43) | MAPTHDAC8MEN1KMT2ACYP2A6 | |
| Benzene SCHEMBL795031 | 0.87 | MAPT (0.50) | MAPTHDAC8ALOX12MDM4TP53 | |
| SCHEMBL3168654 | 0.87 | — | — | |
| SCHEMBL3320886 | 0.87 | MAPT (0.43) | MAPTHDAC8MEN1KMT2ACYP2A6 | |
| SCHEMBL1157899 | 0.87 | — | — | |
| SCHEMBL8609431 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148383-B2 | Low loss high refractive index vinyl sulfide compounds and method of making same | CORNING INCORPORATED (US) | 2006-12-12 | — | — | US | claimed |
| US-20050240060-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | LESLIE THOMAS M | 2005-10-27 | — | — | US | claimed |
| US-20040044251-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | CORNING INCORPORATED | 2004-03-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050240060-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | CRY2, SOS2, CRYZ | MAPT 4416/4885HDAC8 4100/4885MEN1 4251/4885 |
| US-20040044251-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | SOS2, CRY2, PER2 | MAPT 4536/4885HDAC8 4389/4885MEN1 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.