Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847121 | 0.84 | CCR3 (0.35) | CCR3 | |
| SCHEMBL5847619 | 0.84 | CPS1 (0.37) | CCR3 | |
| SCHEMBL5847913 | 0.83 | ABCB1 (0.35) | CCR3 | |
| SCHEMBL5849715 | 0.82 | DRD1 (0.37) | CCR3HCRTR1HCRTR2 | |
| SCHEMBL5418263 | 0.82 | CCR3 (0.38) | CCR3HCRTR1HCRTR2FFAR4 | |
| SCHEMBL5848064 | 0.80 | DPP4 (0.36) | CCR3 | |
| SCHEMBL5847854 | 0.79 | HCRTR1 (0.36) | CCR3HCRTR1HCRTR2 | |
| SCHEMBL5847800 | 0.79 | HTR2A (0.44) | CCR3HCRTR1HCRTR2 | |
| SCHEMBL5847193 | 0.79 | CCR3 (0.35) | CCR3FFAR4 | |
| SCHEMBL5847324 | 0.78 | CCR3 (0.34) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081455-B2 | Substituted heterocycle fused gamma-carbolines | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-25 | — | — | US | claimed |
| US-7081455-B2 | Substituted heterocycle fused gamma-carbolines | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-25 | — | — | US | disclosed |