Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584144 | 0.85 | ELANE (0.51) | HTR1ADRD2FFAR1MAPTTDP1 | |
| SCHEMBL20755877 | 0.81 | FFAR1 (0.57) | HTR1ADRD2FFAR1MAPTTDP1 | |
| SCHEMBL1021663 | 0.80 | CCR5 (0.48) | HTR1ADRD2FFAR1MAPTTDP1 | |
| SCHEMBL10471107 | 0.79 | FFAR1 (0.48) | HTR1ADRD2FFAR1MAPTTDP1 | |
| SCHEMBL561222 | 0.78 | HTR1A (0.67) | HTR1ADRD2MAPTTDP1L3MBTL1 | |
| SCHEMBL4984703 | 0.76 | KMT2A (0.61) | MAPTL3MBTL1ALDH1A1RAB9ALMNA | |
| SCHEMBL3236287 | 0.75 | SLC2A1 (0.52) | MAPTTDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL30758619 | 0.75 | CCR5 (0.56) | CCR5ALDH1A1RAB9ALMNACYP1A2 | |
| SCHEMBL561347 | 0.75 | CCR5 (0.68) | CCR5ALDH1A1RAB9ALMNAMAOB | |
| SCHEMBL30353418 | 0.75 | CCR5 (0.68) | CCR5ALDH1A1RAB9ALMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417119-B1 | NO-CARRIER-ADDED NUCLEOPHILIC ÝF-18¨FLUORINATION OF AROMATIC COMPOUNDS | UNIV CALIFORNIA (US) | 2016-12-21 | — | — | EP | disclosed |
| US-8742139-B2 | No-carrier-added nucleophilic [F-18] fluorination of aromatic compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120123120-A1 | No-Carrier-Added Nucleophilic [F-18] Fluorination of Aromatic Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-17 | — | — | US | disclosed |
| EP-2417119-A2 | NO-CARRIER-ADDED NUCLEOPHILIC ÝF-18¨FLUORINATION OF AROMATIC COMPOUNDS | The Regents of The University of California (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117435-A2 | NO-CARRIER-ADDED NUCLEOPHILIC [F-18] FLUORINATION OF AROMATIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123120-A1 | No-Carrier-Added Nucleophilic [F-18] Fluorination of Aromatic Compounds | SLC18A1, SLC18A2, SLC6A2 | HTR1A 1060/4885DRD2 152/4885FFAR1 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.