SCHEMBL5849966

SCHEMBL5849966

CCc1cc(N)c(C)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.45
RAB9A P51151 3/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
ACHE P22303 1/20 0.37
NPC1 O15118 2/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HSPA5 P11021 1/20 0.36
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ESR1 P03372 3/20 0.34
ESR2 Q92731 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776269 0.84 CYP3A4 (0.39) RAB9AGAAMEN1KMT2ANPC1
SCHEMBL67845 0.84 TRPA1 (0.54) TRPA1RAB9AACHENPC1HPGD
SCHEMBL3226328 0.83 HTT (0.47) TRPA1RAB9AGAAKDM4EMEN1
SCHEMBL29670157 0.79 MAPT (0.45) RAB9AGAAKDM4EMEN1POLB
SCHEMBL109101 0.79 MAPT (0.45) RAB9AGAAKDM4EMEN1POLB
SCHEMBL13384693 0.77 TRPA1 (0.48) TRPA1RAB9AACHENPC1HPGD
SCHEMBL11061127 0.77 SKP2 (0.39) RAB9AGAAMEN1MAPTKMT2A
SCHEMBL6259604 0.76 RAB9A (0.44) RAB9AGAAKDM4EMEN1POLB
SCHEMBL1988566 0.76 TRPA1 (0.46) TRPA1RAB9AGAAMEN1KMT2A
SCHEMBL18951028 0.76 HSPA5 (0.37) GAAMEN1POLBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7070628-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-07-04 US claimed
US-7070627-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-07-04 US claimed
US-7056352-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-06-06 US claimed
EP-1380285-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1374840-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1438948-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1374841-B1 Composition for dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1378229-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-12 EP claimed
US-6852133-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-02-08 US claimed
US-20040139564-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-07-22 US claimed
EP-1438948-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-07-21 EP claimed
US-20040006833-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-01-15 US claimed
EP-1380285-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-14 EP claimed
EP-1378229-A1 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-07 EP claimed
EP-1374840-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-02 EP claimed
EP-1374841-A2 Composition for dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-02 EP claimed
US-20030233715-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US claimed
US-20030233716-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US claimed
US-7070627-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-07-04 US disclosed
US-20030233715-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US disclosed