Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179864 | 0.85 | HTT (0.56) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL29670157 | 0.84 | MAPT (0.45) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL109101 | 0.84 | MAPT (0.45) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL5849966 | 0.83 | TRPA1 (0.45) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL6259604 | 0.81 | RAB9A (0.44) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL21816945 | 0.79 | GABRA1 (0.50) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL23387406 | 0.78 | HTT (0.48) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL20170333 | 0.78 | GABRA1 (0.40) | RAB9ANPC1ALDH1A1MAPTGABRA1 | |
| SCHEMBL31545718 | 0.74 | HTT (0.59) | HTTRAB9ANPC1HPGDMAPK1 | |
| SCHEMBL2786932 | 0.73 | KDM4E (0.63) | HTTRAB9ANPC1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017673-A1 | RESORCINOL AND M-AMINOPHENOL DERIVATIVES BLENDS IN RUBBER COMPOUNDING APPLICATIONS | SINO LEGEND (ZHANGJIAGANG) CHEMICAL CO., LTD (CN) | 2010-02-18 | — | — | WO | disclosed |
| EP-0298704-A2 | Adhesive composition for fibrous materials and process of its preparation | Bridgestone Corporation (JP) | 1989-01-11 | — | — | EP | disclosed |