SCHEMBL109101

SCHEMBL109101

Cc1c(N)cc(CCO)cc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
ALDH1A1 P00352 5/20 0.45
GAA P10253 4/20 0.45
KDM4E B2RXH2 4/20 0.45
ALOX5 P09917 1/20 0.45
BACE1 P56817 1/20 0.45
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPK1 P28482 2/20 0.38
HPGD P15428 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
NPC1 O15118 1/20 0.38
HTT P42858 1/20 0.38
CA2 P00918 2/20 0.35
ACHE P22303 1/20 0.34
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670157 1.00 MAPT (0.45) MAPTALDH1A1GAAKDM4EALOX5
SCHEMBL6259604 0.89 RAB9A (0.44) MAPTALDH1A1GAAKDM4EALOX5
SCHEMBL3226328 0.84 HTT (0.47) MAPTALDH1A1GAAKDM4ERAB9A
Sulfamide SCHEMBL11473316 0.82 CA2 (0.44) MAPTALDH1A1GAAKDM4EALOX5
SCHEMBL5849966 0.79 TRPA1 (0.45) MAPTALDH1A1GAAKDM4EBACE1
SCHEMBL27709558 0.72 ALDH1A1 (0.36) MAPTALDH1A1GAAKDM4EALOX5
SCHEMBL27848436 0.72 ACHE (0.34) MAPTALDH1A1GAAKDM4EALOX5
SCHEMBL4668334 0.71 KDM4E (0.65) MAPTALDH1A1GAAKDM4EALOX5
SCHEMBL18928227 0.71 ALDH1A1 (0.65) MAPTALDH1A1GAAKDM4EALOX5
3,4,5-Trihydroxyphenethyl Alcohol SCHEMBL2990691 0.71 KDM4E (0.58) MAPTALDH1A1GAAKDM4EALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 801 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
WO-2025061319-A2 IMPROVING THE WASHING FASTNESS OF LEVEL 2 COLORATIONS BY MEANS OF A SEALING PROCESS USING SILANES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
EP-4496559-A1 AGENT FOR OXIDATIVE DYEING OF KERATIN FIBRES, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496555-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE P-PHENYLENEDIAMINE TYPE, ISATIN AND AT LEAST ONE OXIDISING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496558-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED ALKALISING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496556-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, AT LEAST ONE OXIDATION DYE PRECURSOR OF THE COUPLER TYPE AND ISATIN Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496557-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED COMPLEXING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
US-20250009629-A1 AGENT FOR OXIDATIVE DYEING OF KERATIN FIBERS, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER HENKEL AG & CO. KGAA (DE) 2025-01-09 US claimed
US-12178897-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-12-31 US claimed
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-08 US claimed
CN-101384240-A Hair colouring compositions PROCTER & GAMBLE (US) 2009-03-11 CN claimed
US-7070628-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-07-04 US claimed
EP-1374841-B1 Composition for dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1378229-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-12 EP claimed
EP-1378229-A1 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-07 EP claimed
EP-1374841-A2 Composition for dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-02 EP claimed
US-20030233716-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US claimed
EP-1197202-B1 Hair dye composition comprising 2,6-diaminopurine KPSS KAO GMBH (DE) 2003-07-09 EP claimed
EP-1201225-B1 Hair dye composition KPSS KAO GMBH (DE) 2003-04-16 EP claimed
EP-1103248-B1 Hair dyeing composition comprising N-ethyl-N-isopropyl-p-phenylenediamine GOLDWELL GMBH (DE) 2001-08-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, ALDH2 MAPT 1335/4885ALDH1A1 40/4885GAA 4422/4885
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer KRT18, ARSA, MKI67 MAPT 3063/4885ALDH1A1 433/4885GAA 1091/4885
US-20250009629-A1 AGENT FOR OXIDATIVE DYEING OF KERATIN FIBERS, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER KRT18, TES, ARSA MAPT 2284/4885ALDH1A1 952/4885GAA 193/4885
US-12178897-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, COX5A MAPT 984/4885ALDH1A1 37/4885GAA 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.