SCHEMBL5850276

SCHEMBL5850276

O=P(Cl)(Cl)C1=C2C=CC=CC2C=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5848486 0.79
SCHEMBL17923692 0.76 ALDH1A1 (0.32)
SCHEMBL5045911 0.73
SCHEMBL9205277 0.73
SCHEMBL11176419 0.68
SCHEMBL6682147 0.68 CYP3A4 (0.31)
SCHEMBL6684629 0.65
SCHEMBL6682019 0.64 CASP3 (0.30)
SCHEMBL11178182 0.63
SCHEMBL27434676 0.61 LMNA (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7112696-B2 Preparation of phosphorus compounds BAYER CHEMICALS AG (DE) 2006-09-26 US disclosed
US-20050020835-A1 Preparation of phosphorus compounds LANXESS DEUTSCHLAND GMBH (DE) 2005-01-27 US disclosed
EP-1475384-A1 Process for preparing phosphorus compounds Bayer Chemicals AG (DE) 2004-11-10 EP disclosed