Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917008 | 0.73 | SMN1; SMN2 (0.36) | HPD | |
| SCHEMBL127232 | 0.72 | HPD (0.36) | HPD | |
| SCHEMBL20917709 | 0.68 | ALDH1A1 (0.40) | — | |
| SCHEMBL20916998 | 0.67 | CNR2 (0.37) | — | |
| SCHEMBL20916988 | 0.66 | KDM4E (0.45) | MAPT | |
| SCHEMBL20916997 | 0.65 | ALDH1A1 (0.45) | — | |
| SCHEMBL20916995 | 0.64 | LMNA (0.46) | MAPT | |
| SCHEMBL21715110 | 0.64 | NPSR1 (0.34) | — | |
| SCHEMBL20917012 | 0.64 | HPD (0.47) | HPDMAPT | |
| SCHEMBL10192391 | 0.64 | HPD (0.44) | HPDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450243-B2 | Herbicidal quinoline and 1,8-naphthyridine compounds | SYNGENTA LIMITED (GB) | 2013-05-28 | — | — | US | disclosed |
| EP-2417132-B1 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | SYNGENTA LTD (GB) | 2013-04-17 | — | — | EP | disclosed |
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| EP-2417132-A2 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | Syngenta Limited (GB) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010116122-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | NQO2, QDPR, CYP4X1 | HPD 39/4885AHR 1760/4885MAPT 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.