Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT5B | P51692 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850900 | 0.86 | CYP1A2 (0.43) | ALDH1A1STAT3MEN1KMT2AL3MBTL1 | |
| SCHEMBL5852329 | 0.81 | PTGES (0.33) | ALDH1A1PTGESSTAT3STAT5BMEN1 | |
| SCHEMBL6636214 | 0.77 | ALDH1A1 (0.34) | ALDH1A1PTGESMEN1KMT2AMAPT | |
| SCHEMBL5850602 | 0.77 | CYP1A2 (0.45) | MEN1KMT2AKDM4EL3MBTL1POLB | |
| SCHEMBL5850697 | 0.77 | CYP1A2 (0.41) | ALDH1A1PKML3MBTL1TP53POLB | |
| SCHEMBL6664426 | 0.76 | ALDH1A1 (0.33) | ALDH1A1PTGESMEN1KMT2AMAPT | |
| SCHEMBL6633734 | 0.76 | ALDH1A1 (0.33) | ALDH1A1PTGESMEN1KMT2AMAPT | |
| SCHEMBL5852118 | 0.75 | PSEN1 (0.35) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL5850614 | 0.73 | PTGES (0.31) | PTGESSTAT3STAT5B | |
| SCHEMBL5850585 | 0.73 | PTGES (0.36) | ALDH1A1PTGESKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030114-B1 | Compounds which inhibit leukocyte adhesion mediated by VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2006-04-18 | — | — | US | claimed |