Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 4/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853975 | 0.87 | PPIA (0.39) | PPIAITGB1ITGA4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5855370 | 0.85 | HPGD (0.40) | KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5855150 | 0.83 | LMNA (0.36) | KMT2ALMNAGAA | |
| Hydrochloric Acid SCHEMBL5853726 | 0.81 | MEN1 (0.39) | MEN1KMT2AMAPTLMNAGAA | |
| Hydrochloric Acid SCHEMBL5853942 | 0.81 | NR1H4 (0.41) | MEN1KMT2ANR1H4LMNAGAA | |
| Hydrochloric Acid SCHEMBL5854920 | 0.81 | CCKBR (0.35) | MEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL5855434 | 0.81 | ITGB1 (0.31) | ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL5855558 | 0.79 | POLB (0.37) | PPIAMEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL5853669 | 0.79 | TAS1R3 (0.38) | PPIAMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5852780 | 0.78 | MEN1 (0.39) | PPIAMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |