Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 6/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482174 | 0.83 | USP30 (0.37) | UCHL1NR1H2 | |
| SCHEMBL6644374 | 0.78 | FFAR1 (0.43) | LIPEP4HBLPLLIPG | |
| SCHEMBL2209141 | 0.77 | UCHL1 (0.34) | UCHL1P4HBLPLLIPG | |
| SCHEMBL32685024 | 0.75 | SCD (0.39) | LIPELPLLIPG | |
| SCHEMBL6644376 | 0.73 | LIPG (0.40) | P4HBLPLLIPG | |
| SCHEMBL1094283 | 0.73 | LPL (0.36) | LPLLIPG | |
| SCHEMBL30241906 | 0.72 | UCHL1 (0.39) | UCHL1LPLLIPGNR1H2 | |
| SCHEMBL18013721 | 0.70 | USP30 (0.36) | UCHL1NR1H2 | |
| SCHEMBL31258155 | 0.70 | USP30 (0.40) | LIPEUCHL1NR1H2 | |
| SCHEMBL32684434 | 0.69 | USP30 (0.36) | UCHL1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |