Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5853672

CCCC(=O)N[Hf+2](C1C=Cc2ccccc21)[SiH](c1ccccc1)c1ccccc1.[Cl-].[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 2/20 0.33
RECQL P46063 1/20 0.33
CYP3A4 P08684 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
TDP2 O95551 1/20 0.30
PAX8 Q06710 1/20 0.30
HKDC1 Q2TB90 1/20 0.30
TLR9 Q9NR96 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5853437 0.93 NPSR1 (0.36) ALDH1A1HPGDL3MBTL1HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL5853441 0.92 EPHX2 (0.38) ALDH1A1RAB9ANPC1HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL5852535 0.91 EPHX2 (0.39) ALDH1A1
Hydrochloric Acid SCHEMBL5854307 0.91 EPHX2 (0.39) ALDH1A1
Hydrochloric Acid SCHEMBL5852693 0.91 SIGMAR1 (0.31) MAPTCYP2C19CYP3A4MAPK1GAA
Hydrochloric Acid SCHEMBL5853659 0.87 ALOX5 (0.34) ALOX5ALDH1A1MAPTHPGDCYP2C19
Hydrochloric Acid SCHEMBL5853701 0.84
Hydrochloric Acid SCHEMBL5853055 0.81
Hydrochloric Acid SCHEMBL5854310 0.81 ATM (0.32) MAPTRAB9ANPC1HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL5855504 0.81 LMNA (0.38) ALDH1A1CYP2C19RAB9ANPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed