Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853050 | 0.90 | ALOX5 (0.38) | MAPTKMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL5854750 | 0.88 | NPSR1 (0.39) | KMT2AMEN1RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL5852985 | 0.87 | SOAT1 (0.43) | KMT2AMEN1RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL5855548 | 0.86 | SOAT1 (0.44) | KMT2AMEN1RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL5853249 | 0.86 | SOAT1 (0.44) | KMT2AMEN1RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL5855900 | 0.85 | POLB (0.37) | MAPTCYP1A2TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5854939 | 0.85 | MAPT (0.36) | MAPTCYP1A2TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5853382 | 0.82 | CCKBR (0.33) | MAPTKMT2AMEN1GAAXBP1 | |
| Hydrochloric Acid SCHEMBL5852952 | 0.81 | GAA (0.38) | MAPTKMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL5853874 | 0.79 | TAS1R3 (0.37) | KMT2AMEN1GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |