SCHEMBL5854010

SCHEMBL5854010

CC=CC(=O)c1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.63
KMT2A Q03164 7/20 0.63
ALDH1A1 P00352 5/20 0.63
F3 P13726 3/20 0.61
RAB9A P51151 4/20 0.56
MAOB P27338 3/20 0.56
MAOA P21397 2/20 0.56
POLB P06746 1/20 0.56
MEN1 O00255 5/20 0.56
CYP3A4 P08684 3/20 0.56
LMNA P02545 3/20 0.56
ESR1 P03372 2/20 0.56
GAA P10253 2/20 0.56
NR3C1 P04150 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
ALOX15 P16050 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11587157 1.00 MAPT (0.63) MAPTKMT2AALDH1A1F3RAB9A
SCHEMBL10694907 0.82 ALDH1A1 (0.52) MAPTKMT2AALDH1A1F3RAB9A
SCHEMBL13519185 0.82 ALDH1A1 (0.78) MAPTKMT2AALDH1A1RAB9AMAOB
SCHEMBL11818123 0.82 ALDH1A1 (0.78) MAPTKMT2AALDH1A1RAB9AMAOB
SCHEMBL11818127 0.82 ALDH1A1 (0.78) MAPTKMT2AALDH1A1RAB9AMAOB
SCHEMBL26976333 0.82 ALDH1A1 (0.52) MAPTKMT2AALDH1A1F3RAB9A
SCHEMBL10694911 0.82 ALDH1A1 (0.52) MAPTKMT2AALDH1A1F3RAB9A
SCHEMBL956091 0.80 CYP1A2 (0.63) MAPTKMT2AALDH1A1RAB9AMAOB
SCHEMBL13960902 0.80 MAPT (0.63) MAPTKMT2AALDH1A1RAB9AMAOB
SCHEMBL22797129 0.80 ALDH1A1 (0.50) MAPTKMT2AALDH1A1F3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115120722-A Use of SP/KLF transcription factor inhibitors 天津医科大学 2022-09-30 CN claimed
CN-115120722-B Use of SP/KLF transcription factor inhibitors 天津医科大学 2024-02-09 CN disclosed
CN-111759827-B A pharmaceutical composition for preventing or treating arthritis or inflammatory diseases 忠北大学校产学协力团 2023-02-07 CN disclosed
CN-115120722-A Use of SP/KLF transcription factor inhibitors 天津医科大学 2022-09-30 CN disclosed
CN-113214114-A Reactive group-blocked diisocyanate for 3D object printing, composition, and method and apparatus for printing 3D object 珠海赛纳三维科技有限公司 2021-08-06 CN disclosed
CN-107438433-B Pharmaceutical composition for preventing and treating arthritis or inflammatory diseases containing 2-methoxy-4- (3- (4-methoxyphenyl) prop-1-en-1-yl) phenol as an active ingredient 忠北大学校产学协力团 2021-06-25 CN disclosed
CN-107090414-B Pesticidal flavobacterium strains 马罗内生物创新公司 2020-12-04 CN disclosed
CN-111759827-A A pharmaceutical composition for preventing or treating arthritis or inflammatory diseases 忠北大学校产学协力团 2020-10-13 CN disclosed
US-7067074-B2 Near-infrared-absorbing composition and optical material KUREHA CORPORATION (JP) 2006-06-27 US disclosed
US-7053231-B2 Building material KUREHA CHEMICAL INDUSTRY COMPANY, LTD. (JP) 2006-05-30 US disclosed
US-20040204600-A1 Building Material KUREHA CHEMICAL INDUSTRY COMPANY, LIMITED 2004-10-14 US disclosed
US-6803367-B2 ANTICANCER AGENTS; SYNERGISTIC MIXTURES TAKARA SHUZO CO., LTD. (JP) 2004-10-12 US disclosed
EP-1447687-A1 BUILDING MATERIAL Kureha Chemical Industry Co., Ltd. (JP) 2004-08-18 EP disclosed
US-20030160217-A1 Near-infrared-absorbing composition and optical material KUREHA CORPORATION (JP) 2003-08-28 US disclosed
US-20030065014-A1 Substance for inducing apoptosis TAKARA BIO INC. (JP) 2003-04-03 US disclosed
EP-1277821-A1 NEAR-INFRARED-ABSORBING COMPOSITION AND OPTICAL MATERIAL KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-01-22 EP disclosed
US-4734471-A Method of curing polyfluoroalkoxyphosphazene ETHYL CORPORATION (US) 1988-03-29 US disclosed
US-4389236-A POSTEMERGENCE CIBA-GEIGY CORPORATION (US) 1983-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065014-A1 Substance for inducing apoptosis BAX, BCL2, BAD MAPT 3068/4885KMT2A 4360/4885ALDH1A1 1247/4885
US-20040204600-A1 Building Material PRPF8, COPS8, COG8 MAPT 631/4885KMT2A 1814/4885ALDH1A1 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.