Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5852840 | 0.81 | CA2 (0.40) | CA2CA1MAPK1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5852782 | 0.77 | HSP90AA1 (0.37) | MAPK1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5855751 | 0.77 | HSP90AA1 (0.37) | MAPK1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5853466 | 0.74 | CA2 (0.41) | CA2CA1MAPK1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5855348 | 0.71 | CA2 (0.41) | CA2CA1MAPK1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5855039 | 0.71 | CA2 (0.40) | CA2CA1MAPK1MEN1ALDH1A1 | |
| 2-Ethylhexanoic Acid SCHEMBL27669448 | 0.66 | CA2 (0.59) | CA2CA1MAPK1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5852825 | 0.66 | TAS1R3 (0.32) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5853693 | 0.64 | NPC1 (0.41) | MAPK1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28688825 | 0.64 | CA2 (0.50) | CA2CA1MAPK1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |