Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853448 | 0.90 | ALOX5 (0.34) | MTNR1AMTNR1BMEN1CYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL5856028 | 0.88 | CETP (0.34) | MEN1CYP1A2TSHRCYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL5855336 | 0.87 | EPHX2 (0.37) | MEN1CYP1A2CYP2C19KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5854462 | 0.86 | MTNR1A (0.33) | MTNR1AMTNR1BMEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL5853746 | 0.86 | EPHX2 (0.39) | MEN1CYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL5855683 | 0.86 | EPHX2 (0.39) | MEN1CYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL5854767 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL5854608 | 0.82 | MEN1 (0.34) | MEN1ALOX15MAPK1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL5853335 | 0.82 | NR3C1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5851523 | 0.80 | HPGD (0.37) | CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |