Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853367 | 0.96 | HSP90AA1 (0.34) | HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL1645502 | 0.95 | HSP90AA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL5853279 | 0.95 | HSP90AA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL2118348 | 0.92 | HDAC3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5853642 | 0.82 | ALDH1A1 (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5855039 | 0.79 | CA2 (0.40) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5854295 | 0.79 | EPHX2 (0.38) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5852944 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5855238 | 0.78 | EPHX2 (0.40) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5854189 | 0.74 | ALOX5 (0.35) | HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |