Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859070 | 0.90 | SMN1; SMN2 (0.45) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL5859035 | 0.89 | HTT (0.41) | TP53PDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL5862104 | 0.84 | PLAUR (0.44) | TP53ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL5860276 | 0.81 | PDE4B (0.43) | TP53ALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL5859955 | 0.79 | CYP2C9 (0.43) | TP53ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL5859916 | 0.77 | RAB9A (0.49) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL5859258 | 0.76 | ALDH1A1 (0.40) | TP53ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL5859907 | 0.75 | RAB9A (0.49) | ALDH1A1KDM4EHPGDHSD17B10CNR1 | |
| SCHEMBL5859144 | 0.74 | EPHX1 (0.43) | TP53PDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL5859316 | 0.74 | CYP1A2 (0.42) | PDCD1CD274ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |