Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859916 | 0.91 | RAB9A (0.49) | RAB9ANPC1L3MBTL1JAK2BTK | |
| SCHEMBL6661310 | 0.91 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL5862104 | 0.91 | PLAUR (0.44) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5859258 | 0.86 | ALDH1A1 (0.40) | RAB9ANPC1L3MBTL1JAK2JAK1 | |
| SCHEMBL5859257 | 0.85 | HTT (0.45) | RAB9ANPC1JAK2JAK1TYK2 | |
| SCHEMBL5858845 | 0.82 | GPR35 (0.47) | ALDH1A1KDM4EHPGD | |
| SCHEMBL5859859 | 0.81 | TDP1 (0.46) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL5859929 | 0.81 | TDP1 (0.41) | RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL7065086 | 0.76 | ALDH1A1 (0.46) | RAB9ANPC1JAK2JAK1TYK2 | |
| SCHEMBL5862246 | 0.76 | CYP2C9 (0.41) | RAB9AMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |