Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 14/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 13/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026674 | 0.85 | ALOX5 (0.59) | PELI1ESR1ESR2CA12ALDH1A1 | |
| SCHEMBL7777398 | 0.80 | ESR1 (0.48) | HSD17B1HSD17B2PELI1ESR1ESR2 | |
| SCHEMBL9440083 | 0.79 | ESR1 (0.46) | CYP3A4ESR1ESR2CA12ALDH1A1 | |
| SCHEMBL17754365 | 0.78 | PELI1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9PELI1 | |
| SCHEMBL8999895 | 0.78 | HSD17B1 (0.52) | HSD17B1HSD17B2CYP3A4CYP2C9PELI1 | |
| SCHEMBL38660243 | 0.77 | HSD17B1 (0.67) | HSD17B1HSD17B2CYP3A4CYP2C9PELI1 | |
| SCHEMBL30032619 | 0.76 | ALOX5 (0.71) | HSD17B1HSD17B2CYP3A4CYP2C9PELI1 | |
| SCHEMBL1851229 | 0.76 | ALOX5 (0.71) | HSD17B1HSD17B2CYP3A4CYP2C9PELI1 | |
| SCHEMBL10306739 | 0.75 | HSD17B1 (0.54) | HSD17B1HSD17B2CYP3A4CYP2C9PELI1 | |
| SCHEMBL8450704 | 0.75 | ALOX5 (0.63) | HSD17B1HSD17B2CYP3A4CYP2C9PELI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057074-B2 | Bisphenylene-spirobifluorene compounds, method for synthesizing the same, and electroluminescence material and device having the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2006-06-06 | — | — | US | disclosed |
| US-6933063-B2 | Spirobifluorene compounds, electroluminescence polymer and electroluminescence element having the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2005-08-23 | — | — | US | disclosed |
| US-6844088-B2 | Bisphenylene-spirobifluorene compounds, method for synthesizing the same, and electroluminescence material and device having the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2005-01-18 | — | — | US | disclosed |
| US-20040034263-A1 | Bisphenylene-spirobifluorene compounds, method for synthesizing the same, and electroluminescence material and device having the same | INTELLECTUAL DISCOVERY CO., LTD. (KR) | 2004-02-19 | — | — | US | disclosed |
| US-20030044642-A1 | Bisphenylene-spirobifluorene compounds, method for synthesizing the same, and electroluminescence material and device having the same | INTELLECTUAL DISCOVERY CO., LTD. (KR) | 2003-03-06 | — | — | US | disclosed |
| US-20030044641-A1 | Spirobifluorene compounds, electroluminescence polymer and electroluminescence element having the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2003-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034263-A1 | Bisphenylene-spirobifluorene compounds, method for synthesizing the same, and electroluminescence material and device having the same | PKD1, NES, EPN1 | HSD17B1 978/4885HSD17B2 870/4885CYP3A4 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.