SCHEMBL5860355

SCHEMBL5860355

O=[N+]([O-])c1ccc(F)cc1COc1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
LMNA P02545 2/20 0.46
SNCA P37840 2/20 0.46
KCNMA1 Q12791 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RAB9A P51151 2/20 0.43
GAA P10253 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 5/20 0.42
HTR1A P08908 1/20 0.42
ADRA1D P25100 1/20 0.42
ADRA1A P35348 1/20 0.42
ADRA1B P35368 1/20 0.42
NPC1 O15118 1/20 0.42
RECQL P46063 1/20 0.42
KDM4E B2RXH2 2/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5594953 0.84 MAOB (0.55) ALDH1A1LMNATDP1MEN1KMT2A
SCHEMBL7158569 0.82 PTGES (0.51) ALDH1A1LMNASNCAATMTDP1
SCHEMBL5860358 0.81 MAOB (0.48) ALDH1A1LMNASNCAATMTDP1
SCHEMBL6823290 0.78 MAOB (0.49) ALDH1A1ATMTDP1MEN1KMT2A
SCHEMBL28035706 0.78 TDP1 (0.56) ALDH1A1SNCAATMTDP1MEN1
SCHEMBL9132620 0.77 TDP1 (0.49) ALDH1A1LMNAKCNMA1ATMTDP1
SCHEMBL7737640 0.75 TDP1 (0.53) ALDH1A1SNCAATMTDP1MEN1
SCHEMBL23536208 0.75 HSPB1 (0.56) ALDH1A1LMNAATMTDP1MEN1
SCHEMBL29447092 0.73 MAPT (0.59) ALDH1A1ATMTDP1MEN1KMT2A
SCHEMBL564270 0.73 MAPT (0.59) ALDH1A1ATMTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060214139-A1 Methods for producing a dielectric, dielectric having self-generating pores, monomer for porous dielectrics, process for preparing poly-o-hydroxyamides, process for preparing ploybenzoxazoles, and processes for producing an electronic component INFINEON TECHNOLOGIES AG 2006-09-28 US disclosed
US-7108807-B2 Methods for producing a dielectric, dielectric having self-generating pores, monomer for porous dielectrics, process for preparing poly-o-hydroxyamides, process for preparing polybenzoxazoles, and processes for producing an electronic component INFINEON TECHNOLOGIES AG (DE) 2006-09-19 US disclosed
US-6861560-B2 Bis-o-aminophenols and processes for producing bis-o-aminophenols INFINEON TECHNOLOGIES AG (DE) 2005-03-01 US disclosed
US-6824949-B2 SELF-CONDENSATION OF AN O-AMINOPHENOLCARBOXYLIC ACID AND REACTION WITH BIS-O-AMINOPHENOLS ALONG WITH DICARBOXYLIC ACID AND ACETYLENE COMPOUNDS; HIGH RESISTANCE AGAINST THE DIFFUSION OF METALS INFINEON TECHNOLOGIES AG (DE) 2004-11-30 US disclosed
US-20040049081-A1 Bis-o-aminophenols and processes for producing bis-o-aminophenols POLARIS INNOVATIONS LIMITED (IE) 2004-03-11 US disclosed
US-20040028821-A1 Methods for producing a dielectric, dielectric having self-generating pores, monomer for porous dielectrics, process for preparing poly-o-hydroxyamides, process for preparing polybenzoxazoles, and processes for producing an electronic component POLARIS INNOVATIONS LIMITED (IE) 2004-02-12 US disclosed
EP-1375471-A1 Bis-o-amino(thio)phenols and their preparation Infineon Technologies AG (DE) 2004-01-02 EP disclosed
EP-1189974-B1 POLYBENZOXAZOLE PRECURSORS INFINEON TECHNOLOGIES AG (DE) 2003-05-21 EP disclosed
US-20020086968-A1 Polybenzoxazole precursors, photoresist solution, polybenzoxazole, and process for preparing a polybenzoxazole precursor POLARIS INNOVATIONS LIMITED (IE) 2002-07-04 US disclosed
EP-1189974-A1 POLYBENZOXAZOLE PRECURSORS Infineon Technologies AG (DE) 2002-03-27 EP disclosed
WO-2001066619-A1 POLYBENZOXAZOLE PRECURSORS INFINEON TECHNOLOGIES AG (DE) 2001-09-13 WO disclosed
EP-1132374-A2 Bis-o-aminophenols and o-aminophenolcarboxylic acids Infineon Technologies AG (DE) 2001-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040049081-A1 Bis-o-aminophenols and processes for producing bis-o-aminophenols DDC, DDT, NDC1 ALDH1A1 672/4885LMNA 2410/4885SNCA 537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.