Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860952 | 0.80 | MALT1 (0.49) | MALT1MTNR1ALMNAPOLBMAPT | |
| SCHEMBL8160279 | 0.79 | GRIA2 (0.44) | CA2 | |
| SCHEMBL27904449 | 0.78 | MTNR1A (0.68) | MALT1MTNR1ALMNACA2POLB | |
| SCHEMBL27904448 | 0.78 | MTNR1A (0.68) | MALT1MTNR1ALMNACA2POLB | |
| SCHEMBL5862052 | 0.74 | DRD2 (0.30) | MTNR1A | |
| SCHEMBL7239677 | 0.73 | HDAC8 (0.46) | — | |
| SCHEMBL21810790 | 0.72 | MALT1 (0.52) | MALT1MTNR1ALMNAPOLBMAPT | |
| SCHEMBL21810794 | 0.72 | MALT1 (0.52) | MALT1MTNR1ALMNAPOLBMAPT | |
| SCHEMBL3983842 | 0.69 | KDM1A (0.40) | MALT1LMNACA2MAPTCYP19A1 | |
| SCHEMBL27534650 | 0.69 | MALT1 (0.38) | MALT1LMNACA2MAPTPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053223-B2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040181068-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181068-A1 | Inhibitors of farnesyl protein transferase | FNTA, FNTB, ACAT2 | MALT1 2972/4885MTNR1A 3879/4885LMNA 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.