SCHEMBL586128

SCHEMBL586128

CC(C)=CCC/C(C)=C/CCO

nearest known ligand 0.78

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SQLE Q14534 7/20 0.78
KMT2A Q03164 3/20 0.76
MAPT P10636 2/20 0.74
MEN1 O00255 2/20 0.74
CYP3A4 P08684 2/20 0.74
ALOX15 P16050 2/20 0.74
ALDH1A1 P00352 1/20 0.74
UGT1A1 P22309 1/20 0.74
ICMT O60725 1/20 0.62
KDM4E B2RXH2 1/20 0.59
FNTA P49354 1/20 0.53
FNTB P49356 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5595473 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL18037035 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL8512384 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL9738963 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL17312900 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL2636615 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL19228659 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL1105229 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL5595479 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4
SCHEMBL7299170 1.00 SQLE (0.78) SQLEKMT2AMAPTMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2134377-B1 FRAGRANCE DISPENSER SYMRISE AG (DE) 2012-07-18 EP claimed
EP-2072083-B1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma SYMRISE AG (DE) 2012-02-15 EP claimed
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE SYMRISE GMBH & CO. KG (DE) 2009-06-25 US claimed
EP-2072083-A1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma Symrise GmbH & Co. KG (DE) 2009-06-24 EP claimed
EP-1682230-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES Symrise GmbH & Co. KG (DE) 2006-07-26 EP claimed
WO-2005004825-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES SYMRISE GMBH & CO. KG (DE) 2005-01-20 WO claimed
US-12391965-B2 Conversion of farnesylacetone to homofarnesylacetate by baeyer-villiger monooxygenase GIVAUDAN SA (CH) 2025-08-19 US disclosed
EP-4267547-B1 PROCESS OF MAKING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-02-05 EP disclosed
US-20240417359-A1 PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2024-12-19 US disclosed
EP-4419498-A1 PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS Givaudan SA (CH) 2024-08-28 EP disclosed
CN-118119589-A Phenol aromatic compound precursor 奇华顿股份有限公司 2024-05-31 CN disclosed
US-20240059636-A1 PROCESS OF MAKING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-02-22 US disclosed
US-20240051904-A1 PROCESS OF MAKING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-02-15 US disclosed
EP-0983989-B1 Methylcyclotetradec-5-ene-1-one GIVAUDAN SA (CH) 2002-03-27 EP disclosed
EP-0884315-B1 Dioxacycloalkan-8-ones GIVAUDAN SA (CH) 2001-09-19 EP disclosed
EP-0983989-A1 Methylcyclotetradec-5-ene-1-one Givaudan Roure (International) S.A. (CH) 2000-03-08 EP disclosed
EP-0908455-A1 Macrocycles GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1999-04-14 EP disclosed
EP-0884315-A1 Dioxacycloalkan-8-ones GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1998-12-16 EP disclosed
EP-0859003-A2 thiamacrolides GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1998-08-19 EP disclosed
US-4137273-A INSECTICIDES, CHEMICAL INTERMEDIATES ZOECON CORPORATION (US) 1979-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE CYP1B1, CYP4A22, ROS1 SQLE 1065/4885KMT2A 585/4885MAPT 2104/4885
US-20240051904-A1 PROCESS OF MAKING ORGANIC COMPOUNDS FDPS, HMGCR, SQLE SQLE 3/4885KMT2A 4573/4885MAPT 4625/4885
US-20240417359-A1 PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS HAAO, FOS, HPD SQLE 353/4885KMT2A 1553/4885MAPT 1624/4885
US-20240059636-A1 PROCESS OF MAKING ORGANIC COMPOUNDS POR, CYC1, CYP11B1 SQLE 7/4885KMT2A 4192/4885MAPT 4093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.