SCHEMBL5862002

SCHEMBL5862002

CCCCOc1ccc(C(C)(C)C)cc1S(=O)(=O)C(=[N+]=[N-])C(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 3/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.39
LMNA P02545 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
WDR5 P61964 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPT P10636 2/20 0.36
PTPN11 Q06124 1/20 0.35
KAT6A Q92794 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
CYP2C19 P33261 1/20 0.35
TRPV1 Q8NER1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5862942 0.97 PTPN11 (0.39) NR1I2PTGDR2LMNAMRGPRX4WDR5
SCHEMBL5862965 0.96 PTPN11 (0.41) NR1I2MRGPRX4KDM4EGAASMN1; SMN2
SCHEMBL5862983 0.89 ENPP1 (0.39) NR1I2PTGDR2GAATDP1L3MBTL1
SCHEMBL5862526 0.88 WDR5 (0.40) LMNAWDR5KDM4EGAASMN1; SMN2
SCHEMBL5861730 0.87 PTPN1 (0.39) NR1I2
SCHEMBL5845465 0.87 PLA2G4B (0.43) WDR5PTPN11KAT6APPARG
SCHEMBL5862941 0.86 PTPN1 (0.40) ALDH1A1
SCHEMBL5861740 0.85 ALDH1A1 (0.38) NR1I2PTGDR2KDM4EGAASMN1; SMN2
SCHEMBL5862927 0.84 PTPN11 (0.40) LMNAWDR5KDM4EGAASMN1; SMN2
SCHEMBL5862527 0.84 PTPN11 (0.42) WDR5ALDH1A1PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109311-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-09-19 US disclosed
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process POLL, VEGFA, PIM3 NR1I2 4388/4885PTGDR2 2724/4885LMNA 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.