SCHEMBL586238

SCHEMBL586238

COc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(N)=O)c(C(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.52
FLT1 P17948 2/20 0.50
FLT4 P35916 2/20 0.50
KDR P35968 2/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
HTT P42858 1/20 0.49
ALDH1A1 P00352 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KDM4E B2RXH2 1/20 0.48
HSD17B10 Q99714 1/20 0.48
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CTSD P07339 1/20 0.45
CAMKK2 Q96RR4 3/20 0.45
MAPK8 P45983 2/20 0.45
PIK3CG P48736 2/20 0.45
GSK3B P49841 2/20 0.43
THRB P10828 1/20 0.43
CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16618816 0.81 CA1 (0.46) KAT6AKCNK3KCNK9ALDH1A1SMN1; SMN2
SCHEMBL4592303 0.81 FLT1 (0.48) KAT6AFLT1FLT4KDRALDH1A1
SCHEMBL18803129 0.80 POLB (0.64) KAT6AFLT1FLT4KDRSMN1; SMN2
Formamide SCHEMBL28301130 0.77 FLT1 (0.52) KAT6AFLT1FLT4KDRKCNK3
SCHEMBL7797528 0.77 GAA (0.59) KAT6AFLT1FLT4KDRALDH1A1
SCHEMBL9414560 0.77 POLB (0.68) KAT6AFLT1FLT4KDRHTT
SCHEMBL16244081 0.76 KDM4E (0.62) KAT6AFLT1FLT4KDRKCNK3
SCHEMBL29288345 0.76 SMN1; SMN2 (0.44) KCNK3KCNK9ALDH1A1SMN1; SMN2KDM4E
SCHEMBL15495162 0.75 RXFP1 (0.60) FLT1FLT4KDRHTTALDH1A1
SCHEMBL125423 0.75 L3MBTL1 (0.54) KAT6AFLT1FLT4KDRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023222831-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-11-23 WO disclosed
EP-4195929-A1 HERBICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2023-06-21 EP disclosed
WO-2022033893-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-02-17 WO disclosed
EP-3920700-A1 HERBICIDAL MIXTURES Syngenta Crop Protection AG (CH) 2021-12-15 EP disclosed
EP-3890487-A1 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-13 EP disclosed
WO-2021013969-A1 3-[(HYDRAZONO)METHYL]-N-(TETRAZOL-5-YL)-BENZAMIDE AND 3-[(HYDRAZONO)METHYL]-N-(1,3,4-OXADIAZOL-2-YL)-BENZAMIDE DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-01-28 WO disclosed
EP-3740470-A1 AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES Syngenta Crop Protection AG (CH) 2020-11-25 EP disclosed
WO-2020161147-A1 HERBICIDAL MIXTURES SYNGENTA CROP PROTECTION AG (CH) 2020-08-13 WO disclosed
WO-2020114869-A1 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2020-06-11 WO disclosed
WO-2019141740-A1 AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2019-07-25 WO disclosed
WO-2012045721-A2 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2012-04-12 WO disclosed
CN-102395568-A Pyrimidine derivatives and their use as herbicides SYNGENTA LTD 2012-03-28 CN disclosed
EP-2417132-A2 HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS Syngenta Limited (GB) 2012-02-15 EP disclosed
WO-2011045561-A2 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2011-04-21 WO disclosed
EP-2265120-A1 HERBICIDAL COUMPOUNDS Syngenta Limited (GB) 2010-12-29 EP disclosed
WO-2010116122-A2 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2010-10-14 WO disclosed
WO-2010112826-A2 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2010-10-07 WO disclosed
WO-2009115788-A1 HERBICIDAL COUMPOUNDS SYNGENTA LIMITED (GB) 2009-09-24 WO disclosed
EP-1755397-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2007-02-28 EP disclosed
WO-2005104848-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-11-10 WO disclosed