Formamide

Formamide

SCHEMBL28301130

COc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(C)C)cc1.NC=O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 4/20 0.52
FLT4 P35916 4/20 0.52
KDR P35968 4/20 0.52
GAA P10253 1/20 0.51
HPGD P15428 2/20 0.49
XBP1 P17861 1/20 0.49
KAT6A Q92794 2/20 0.48
ALDH1A1 P00352 1/20 0.47
CTSD P07339 1/20 0.47
POLB P06746 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
THRB P10828 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
EGFR P00533 1/20 0.43
KCNA3 P22001 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7797528 0.84 GAA (0.59) FLT1FLT4KDRGAAKAT6A
SCHEMBL9414560 0.81 POLB (0.68) FLT1FLT4KDRGAAKAT6A
SCHEMBL16244081 0.81 KDM4E (0.62) FLT1FLT4KDRGAAHPGD
SCHEMBL28301129 0.81 GAA (0.50) FLT1FLT4KDRGAAHPGD
SCHEMBL125423 0.80 L3MBTL1 (0.54) FLT1FLT4KDRGAAHPGD
SCHEMBL877342 0.80 GAA (0.49) FLT1FLT4KDRGAAHPGD
SCHEMBL18803129 0.79 POLB (0.64) FLT1FLT4KDRGAAKAT6A
SCHEMBL27573936 0.78 GAA (0.50) FLT1FLT4KDRGAAHPGD
SCHEMBL16634981 0.78 GAA (0.57) FLT1FLT4KDRGAAHPGD
SCHEMBL586238 0.77 KAT6A (0.52) FLT1FLT4KDRGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890796-A Weeding pyridazinone compound 先正达参股股份有限公司 2019-06-14 CN disclosed