Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.46 |
| ▸ | FABP3 | P05413 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162818 | 0.80 | FABP4 (0.67) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL7974947 | 0.79 | FABP4 (0.46) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL8172825 | 0.71 | FABP4 (0.58) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL8675650 | 0.70 | FABP4 (0.53) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL2946584 | 0.70 | FABP4 (0.62) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL21297046 | 0.69 | FABP4 (0.51) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL14949312 | 0.69 | FABP4 (0.60) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL8989764 | 0.67 | FABP4 (0.69) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL24928405 | 0.67 | FABP4 (0.58) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL17131628 | 0.67 | FABP4 (0.58) | FABP4FABP3FABP5ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39355-E1 | Preparation of human IGF via recombinant DNA technology | GENETECH, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-6331414-B1 | GENERATING INSULIN LIKE GROWTH FACTOR; CONSTRUCT EXPRESSION VECTOR, TRANSFORM PROKARYOTIC CELL, CULTURE CELLS, RECOVER INSULIN LIKE GROWTH FACTOR | GENENTECH, INC. | 2001-12-18 | — | — | US | disclosed |
| US-6331609-B1 | FUSION PROTEIN; FOR USE IN TREATMENT OF SOMATOTROPIN DEFECTS | GENENTECH, INC. | 2001-12-18 | — | — | US | disclosed |