SCHEMBL5864012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5863594	0.91	HRH3 (0.49)	MMP1MMP9MMP13ADAM17LTA4H
	SCHEMBL5863843	0.90	NR3C1 (0.50)	NR3C1MMP1MMP9MMP13ADAM17
	SCHEMBL5863692	0.90	MMP1 (0.51)	MMP1MMP9MMP13ADAM17LTA4H
	SCHEMBL5863623	0.89	NR3C1 (0.53)	NR3C1SERPINE1MMP1MMP9MMP13
	SCHEMBL5863789	0.89	LTA4H (0.53)	NR3C1MMP1MMP9MMP13ADAM17
	SCHEMBL5863649	0.89	MMP1 (0.51)	NR3C1MMP1MMP9MMP13ADAM17
	SCHEMBL5864250	0.89	MMP1 (0.51)	NR3C1MMP1MMP9MMP13ADAM17
	SCHEMBL5863991	0.89	NR3C1 (0.50)	NR3C1MMP1MMP9MMP13ADAM17
	SCHEMBL5863389	0.89	MMP1 (0.57)	NR3C1MMP1MMP9MMP13ADAM17
	SCHEMBL5863913	0.88	KDM4E (0.52)	MMP1MMP9MMP13ADAM17LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.