Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864243 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL5864015 | 0.82 | MMP1 (0.47) | KDM4ELMNAKMT2A | |
| SCHEMBL5864018 | 0.82 | MMP1 (0.47) | KDM4ELMNAKMT2A | |
| SCHEMBL5864179 | 0.81 | SIGMAR1 (0.42) | ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL5864491 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL5864494 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL5863737 | 0.80 | AKR1C3 (0.41) | ALDH1A1LMNA | |
| SCHEMBL5863735 | 0.80 | AKR1C3 (0.41) | ALDH1A1LMNA | |
| SCHEMBL5864062 | 0.79 | MAPT (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL5864066 | 0.79 | MAPT (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053212-B2 | Acyclic amide and sulfonamide ligands for the estrogen receptor | PFIZER INC. (US) | 2006-05-30 | — | — | US | disclosed |