Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.44 |
| ▸ | ITGAL | P20701 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864494 | 1.00 | ALDH1A1 (0.57) | ALDH1A1ITGB2ICAM1ITGALLMNA | |
| SCHEMBL5864015 | 0.84 | MMP1 (0.47) | LMNAMAPTKMT2AMEN1KDM4E | |
| SCHEMBL5864018 | 0.84 | MMP1 (0.47) | LMNAMAPTKMT2AMEN1KDM4E | |
| SCHEMBL5864248 | 0.80 | ALDH1A1 (0.47) | ALDH1A1ICAM1LMNAHDAC1KMT2A | |
| SCHEMBL5864243 | 0.80 | ALDH1A1 (0.47) | ALDH1A1ICAM1LMNAHDAC1KMT2A | |
| SCHEMBL5863737 | 0.78 | AKR1C3 (0.41) | ALDH1A1LMNAMAPT | |
| SCHEMBL5863735 | 0.78 | AKR1C3 (0.41) | ALDH1A1LMNAMAPT | |
| SCHEMBL5863722 | 0.77 | MMP1 (0.47) | LMNAHDAC1KMT2AMEN1 | |
| SCHEMBL5863717 | 0.77 | MMP1 (0.47) | LMNAHDAC1KMT2AMEN1 | |
| SCHEMBL5864173 | 0.77 | NR1H4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053212-B2 | Acyclic amide and sulfonamide ligands for the estrogen receptor | PFIZER INC. (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040110767-A1 | Acyclic amide and sulfonamide ligands for the estrogen receptor | PFIZER INC | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110767-A1 | Acyclic amide and sulfonamide ligands for the estrogen receptor | GHSR, GPER1, SSTR1 | ALDH1A1 2596/4885ITGB2 3991/4885ICAM1 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.