Dasb

Dasb

SCHEMBL586446

CN(C)Cc1ccccc1Sc1ccc(C#N)cc1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 17/20 1.00
SLC6A2 P23975 16/20 1.00
SLC6A3 Q01959 9/20 1.00
TDP1 Q9NUW8 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dasb SCHEMBL29380613 1.00 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
Dasb SCHEMBL29459573 1.00 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
Dasb SCHEMBL29689760 1.00 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL32890246 0.83 SLC6A4 (0.70) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL1645160 0.81 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL29993160 0.81 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL30543447 0.81 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL1644204 0.81 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL8533846 0.80 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL12728082 0.80 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727538-A2 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2026-04-22 EP disclosed
US-20260102372-A1 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2026-04-16 US disclosed
WO-2024259343-A2 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2024-12-19 WO disclosed
US-20240009332-A1 COMPOSITE EMBOLIZATION BEADS TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC 2024-01-11 US disclosed
US-11712487-B2 Composite embolization beads RAIKA MEDICAL IMAGING INC. (US) 2023-08-01 US disclosed
US-20220040335-A1 RADIOLABELED PABA AND DERIVATIVES THEREOF FOR USE AS FUNCTIONAL RENAL IMAGING AGENTS THE JOHNS HOPKINS UNIVERSITY 2022-02-10 US disclosed
US-20210346526-A1 NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION FIVE ELEVEN PHARMA INC. 2021-11-11 US disclosed
US-11071794-B2 Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application FIVE ELEVEN PHARMA INC. (US) 2021-07-27 US disclosed
US-10912849-B2 Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application FIVE ELEVEN PHARMA INC. (US) 2021-02-09 US disclosed
US-20200230263-A1 NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION FIVE ELEVEN PHARMA INC. (US) 2020-07-23 US disclosed
EP-2417124-B1 Serotonin and norepinephrine reuptake inhibitor LILLY CO ELI (US) 2013-12-18 EP disclosed
US-8173821-B2 Serotonin and norepinephrine reuptake inhibitor ELI LILLY AND COMPANY (US) 2012-05-08 US disclosed
EP-2417124-A2 SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR Eli Lilly and Company (US) 2012-02-15 EP disclosed
US-20110097274-A1 Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-04-28 US disclosed
WO-2010117979-A2 SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR ELI LILLY AND COMPANY (US) 2010-10-14 WO disclosed
US-20100261762-A1 SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR ELI LILLY AND COMPANY (US) 2010-10-14 US disclosed
WO-2006117218-A2 SEROTONIN-TRANSPORT-PROTEIN BINDING RADIOPHARMACEUTICAL FOR THE PRODUCTION OF A DIAGNOSTIC MEDICAMENT FOR THE DIAGNOSIS OF HEADACHE CHARITE UNIVERSITÄTSMEDIZIN - BERLIN (DE) 2006-11-09 WO disclosed
EP-1519917-A4 CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS UNIV COLUMBIA (US) 2006-05-17 EP disclosed
EP-1519917-A2 CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2005-04-06 EP disclosed
WO-2003096978-A2 CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2003-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11071794-B2 Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application SLC18A2, SLC6A3, SLC6A2 SLC6A4 4/4885SLC6A2 3/4885SLC6A3 2/4885
US-20200230263-A1 NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION SLC18A2, SLC6A3, SLC6A2 SLC6A4 4/4885SLC6A2 3/4885SLC6A3 2/4885
US-20210346526-A1 NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION SLC18A2, SLC6A3, SLC6A2 SLC6A4 4/4885SLC6A2 3/4885SLC6A3 2/4885
US-10912849-B2 Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application SLC18A2, SLC6A3, SLC6A2 SLC6A4 4/4885SLC6A2 3/4885SLC6A3 2/4885
US-20110097274-A1 Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters SLC6A4, SLC18A2, SLC6A2 SLC6A4 1/4885SLC6A2 3/4885SLC6A3 6/4885
US-20100261762-A1 SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR SLC6A2, SLC6A4, TPH1 SLC6A4 2/4885SLC6A2 1/4885SLC6A3 4/4885
US-20220040335-A1 RADIOLABELED PABA AND DERIVATIVES THEREOF FOR USE AS FUNCTIONAL RENAL IMAGING AGENTS PABPC1, HNRNPAB, HNRNPA1 SLC6A4 3948/4885SLC6A2 3600/4885SLC6A3 3496/4885
US-20260102372-A1 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT SLC6A4, SLC6A2, SLC6A3 SLC6A4 1/4885SLC6A2 2/4885SLC6A3 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.